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DprE1 Is a Vulnerable Tuberculosis Drug Target Due to Its Cell Wall Localization.
ACS Chem Biol. 2015 Jul 17;10(7):1631-6. doi: 10.1021/acschembio.5b00237. Epub 2015 Apr 29.
ACS Chem Biol. 2015.
PMID: 25906160
The 8-Pyrrole-Benzothiazinones Are Noncovalent Inhibitors of DprE1 from Mycobacterium tuberculosis.
Makarov V, Neres J, Hartkoorn RC, Ryabova OB, Kazakova E, Šarkan M, Huszár S, Piton J, Kolly GS, Vocat A, Conroy TM, Mikušová K, Cole ST.
Makarov V, et al. Among authors: sarkan m.
Antimicrob Agents Chemother. 2015 Aug;59(8):4446-52. doi: 10.1128/AAC.00778-15. Epub 2015 May 18.
Antimicrob Agents Chemother. 2015.
PMID: 25987616
Free PMC article.
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Development of 3,5-Dinitrobenzylsulfanyl-1,3,4-oxadiazoles and Thiadiazoles as Selective Antitubercular Agents Active Against Replicating and Nonreplicating Mycobacterium tuberculosis.
Karabanovich G, Zemanová J, Smutný T, Székely R, Šarkan M, Centárová I, Vocat A, Pávková I, Čonka P, Němeček J, Stolaříková J, Vejsová M, Vávrová K, Klimešová V, Hrabálek A, Pávek P, Cole ST, Mikušová K, Roh J.
Karabanovich G, et al. Among authors: sarkan m.
J Med Chem. 2016 Mar 24;59(6):2362-80. doi: 10.1021/acs.jmedchem.5b00608. Epub 2016 Mar 15.
J Med Chem. 2016.
PMID: 26948407
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Design, Syntheses, and Anti-TB Activity of 1,3-Benzothiazinone Azide and Click Chemistry Products Inspired by BTZ043.
Tiwari R, Miller PA, Chiarelli LR, Mori G, Šarkan M, Centárová I, Cho S, Mikušová K, Franzblau SG, Oliver AG, Miller MJ.
Tiwari R, et al. Among authors: sarkan m.
ACS Med Chem Lett. 2016 Jan 4;7(3):266-70. doi: 10.1021/acsmedchemlett.5b00424. eCollection 2016 Mar 10.
ACS Med Chem Lett. 2016.
PMID: 26985313
Free PMC article.
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