Structure-relaxation mechanism for the response of T4 lysozyme cavity mutants to hydrostatic pressure.
Lerch MT, López CJ, Yang Z, Kreitman MJ, Horwitz J, Hubbell WL.
Lerch MT, et al. Among authors: lopez cj.
Proc Natl Acad Sci U S A. 2015 May 12;112(19):E2437-46. doi: 10.1073/pnas.1506505112. Epub 2015 Apr 27.
Proc Natl Acad Sci U S A. 2015.
PMID: 25918400
Free PMC article.
A current view is that the volume reduction is dominated by elimination of voids or cavities in the protein interior via cavity hydration, although an alternative mechanism wherein cavities are filled with protein side chains resulting from a structure relaxation has been suggest …
A current view is that the volume reduction is dominated by elimination of voids or cavities in the protein interior via cavity hydration, a …