Yuan TL - Search Results

1

The Endoplasmic Reticulum Stress Sensor IRE1α in Intestinal Epithelial Cells Is Essential for Protecting against Colitis.

Zhang HS, Chen Y, Fan L, Xi QL, Wu GH, Li XX, Yuan TL, He SQ, Yu Y, Shao ML, Liu Y, Bai CG, Ling ZQ, Li M, Liu Y, Fang J. Zhang HS, et al. Among authors: yuan tl. J Biol Chem. 2015 Jun 12;290(24):15327-36. doi: 10.1074/jbc.M114.633560. Epub 2015 Apr 29. J Biol Chem. 2015. PMID: 25925952 Free PMC article.

2

PHD3 Stabilizes the Tight Junction Protein Occludin and Protects Intestinal Epithelial Barrier Function.

Chen Y, Zhang HS, Fong GH, Xi QL, Wu GH, Bai CG, Ling ZQ, Fan L, Xu YM, Qin YQ, Yuan TL, Sun H, Fang J. Chen Y, et al. Among authors: yuan tl. J Biol Chem. 2015 Aug 14;290(33):20580-9. doi: 10.1074/jbc.M115.653584. Epub 2015 Jun 29. J Biol Chem. 2015. PMID: 26124271 Free PMC article.

3

Prolyl hydroxylase 2 is dispensable for homeostasis of intestinal epithelium in mice.

Xie Y, Yuan T, Qin Y, Weng Z, Fang J. Xie Y, et al. Acta Biochim Biophys Sin (Shanghai). 2018 Jun 1;50(6):540-546. doi: 10.1093/abbs/gmy037. Acta Biochim Biophys Sin (Shanghai). 2018. PMID: 29688249 Free article.

4

PHD3 inhibits colon cancer cell metastasis through the occludin-p38 pathway.

Li Y, Yuan T, Zhang H, Liu S, Lun J, Guo J, Wang Y, Zhang Y, Fang J. Li Y, et al. Acta Biochim Biophys Sin (Shanghai). 2023 Nov 25;55(11):1749-1757. doi: 10.3724/abbs.2023103. Acta Biochim Biophys Sin (Shanghai). 2023. PMID: 37814811 Free PMC article.

5

A rationally engineered cytosine base editor retains high on-target activity while reducing both DNA and RNA off-target effects.

Zuo E, Sun Y, Yuan T, He B, Zhou C, Ying W, Liu J, Wei W, Zeng R, Li Y, Yang H. Zuo E, et al. Nat Methods. 2020 Jun;17(6):600-604. doi: 10.1038/s41592-020-0832-x. Epub 2020 May 18. Nat Methods. 2020. PMID: 32424272

6

Programmable RNA editing with compact CRISPR-Cas13 systems from uncultivated microbes.

Xu C, Zhou Y, Xiao Q, He B, Geng G, Wang Z, Cao B, Dong X, Bai W, Wang Y, Wang X, Zhou D, Yuan T, Huo X, Lai J, Yang H. Xu C, et al. Nat Methods. 2021 May;18(5):499-506. doi: 10.1038/s41592-021-01124-4. Epub 2021 May 3. Nat Methods. 2021. PMID: 33941935

7

Author Correction: Programmable RNA editing with compact CRISPR-Cas13 systems from uncultivated microbes.

Xu C, Zhou Y, Xiao Q, He B, Geng G, Wang Z, Cao B, Dong X, Bai W, Wang Y, Wang X, Zhou D, Yuan T, Huo X, Lai J, Yang H. Xu C, et al. Nat Methods. 2022 Feb;19(2):255. doi: 10.1038/s41592-021-01379-x. Nat Methods. 2022. PMID: 34975157 No abstract available.

8

GOTI, a method to identify genome-wide off-target effects of genome editing in mouse embryos.

Zuo E, Sun Y, Wei W, Yuan T, Ying W, Sun H, Yuan L, Steinmetz LM, Li Y, Yang H. Zuo E, et al. Nat Protoc. 2020 Sep;15(9):3009-3029. doi: 10.1038/s41596-020-0361-1. Epub 2020 Aug 14. Nat Protoc. 2020. PMID: 32796939 Free PMC article.

9

Cytosine base editor generates substantial off-target single-nucleotide variants in mouse embryos.

Zuo E, Sun Y, Wei W, Yuan T, Ying W, Sun H, Yuan L, Steinmetz LM, Li Y, Yang H. Zuo E, et al. Science. 2019 Apr 19;364(6437):289-292. doi: 10.1126/science.aav9973. Epub 2019 Feb 28. Science. 2019. PMID: 30819928 Free PMC article.

10

Cytosine base editors induce off-target mutations and adverse phenotypic effects in transgenic mice.

Yan N, Feng H, Sun Y, Xin Y, Zhang H, Lu H, Zheng J, He C, Zuo Z, Yuan T, Li N, Xie L, Wei W, Sun Y, Zuo E. Yan N, et al. Nat Commun. 2023 Mar 30;14(1):1784. doi: 10.1038/s41467-023-37508-7. Nat Commun. 2023. PMID: 36997536 Free PMC article.

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