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Synergistic Leukemia Eradication by Combined Treatment with Retinoic Acid and HIF Inhibition by EZN-2208 (PEG-SN38) in Preclinical Models of PML-RARα and PLZF-RARα-Driven Leukemia.
Clin Cancer Res. 2015 Aug 15;21(16):3685-94. doi: 10.1158/1078-0432.CCR-14-3022. Epub 2015 Apr 30.
Clin Cancer Res. 2015.
PMID: 25931453
HIF-1α regulates the interaction of chronic lymphocytic leukemia cells with the tumor microenvironment.
Valsecchi R, Coltella N, Belloni D, Ponente M, Ten Hacken E, Scielzo C, Scarfò L, Bertilaccio MT, Brambilla P, Lenti E, Martinelli Boneschi F, Brendolan A, Ferrero E, Ferrarini M, Ghia P, Tonon G, Ponzoni M, Caligaris-Cappio F, Bernardi R.
Valsecchi R, et al. Among authors: ponente m.
Blood. 2016 Apr 21;127(16):1987-97. doi: 10.1182/blood-2015-07-657056. Epub 2016 Jan 29.
Blood. 2016.
PMID: 26825709
Free PMC article.
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PML promotes metastasis of triple-negative breast cancer through transcriptional regulation of HIF1A target genes.
Ponente M, Campanini L, Cuttano R, Piunti A, Delledonne GA, Coltella N, Valsecchi R, Villa A, Cavallaro U, Pattini L, Doglioni C, Bernardi R.
Ponente M, et al.
JCI Insight. 2017 Feb 23;2(4):e87380. doi: 10.1172/jci.insight.87380.
JCI Insight. 2017.
PMID: 28239645
Free PMC article.
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