Gagnon JA - Search Results

1

Efficient CRISPR-Cas9-mediated generation of knockin human pluripotent stem cells lacking undesired mutations at the targeted locus.

Merkle FT, Neuhausser WM, Santos D, Valen E, Gagnon JA, Maas K, Sandoe J, Schier AF, Eggan K. Merkle FT, et al. Among authors: gagnon ja. Cell Rep. 2015 May 12;11(6):875-883. doi: 10.1016/j.celrep.2015.04.007. Epub 2015 Apr 30. Cell Rep. 2015. PMID: 25937281 Free PMC article.

2

Toddler: an embryonic signal that promotes cell movement via Apelin receptors.

Pauli A, Norris ML, Valen E, Chew GL, Gagnon JA, Zimmerman S, Mitchell A, Ma J, Dubrulle J, Reyon D, Tsai SQ, Joung JK, Saghatelian A, Schier AF. Pauli A, et al. Among authors: gagnon ja. Science. 2014 Feb 14;343(6172):1248636. doi: 10.1126/science.1248636. Epub 2014 Jan 9. Science. 2014. PMID: 24407481 Free PMC article.

3

CHOPCHOP: a CRISPR/Cas9 and TALEN web tool for genome editing.

Montague TG, Cruz JM, Gagnon JA, Church GM, Valen E. Montague TG, et al. Among authors: gagnon ja. Nucleic Acids Res. 2014 Jul;42(Web Server issue):W401-7. doi: 10.1093/nar/gku410. Epub 2014 May 26. Nucleic Acids Res. 2014. PMID: 24861617 Free PMC article.

4

Efficient mutagenesis by Cas9 protein-mediated oligonucleotide insertion and large-scale assessment of single-guide RNAs.

Gagnon JA, Valen E, Thyme SB, Huang P, Akhmetova L, Pauli A, Montague TG, Zimmerman S, Richter C, Schier AF. Gagnon JA, et al. PLoS One. 2014 May 29;9(5):e98186. doi: 10.1371/journal.pone.0098186. eCollection 2014. PLoS One. 2014. PMID: 24873830 Free PMC article.

5

Evolutionarily conserved regulation of hypocretin neuron specification by Lhx9.

Liu J, Merkle FT, Gandhi AV, Gagnon JA, Woods IG, Chiu CN, Shimogori T, Schier AF, Prober DA. Liu J, et al. Among authors: gagnon ja. Development. 2015 Mar 15;142(6):1113-24. doi: 10.1242/dev.117424. Epub 2015 Feb 27. Development. 2015. PMID: 25725064 Free PMC article.

6

CHOPCHOP v2: a web tool for the next generation of CRISPR genome engineering.

Labun K, Montague TG, Gagnon JA, Thyme SB, Valen E. Labun K, et al. Among authors: gagnon ja. Nucleic Acids Res. 2016 Jul 8;44(W1):W272-6. doi: 10.1093/nar/gkw398. Epub 2016 May 16. Nucleic Acids Res. 2016. PMID: 27185894 Free PMC article.

7

Whole-organism lineage tracing by combinatorial and cumulative genome editing.

McKenna A, Findlay GM, Gagnon JA, Horwitz MS, Schier AF, Shendure J. McKenna A, et al. Among authors: gagnon ja. Science. 2016 Jul 29;353(6298):aaf7907. doi: 10.1126/science.aaf7907. Epub 2016 May 26. Science. 2016. PMID: 27229144 Free PMC article.

8

Toddler signaling regulates mesodermal cell migration downstream of Nodal signaling.

Norris ML, Pauli A, Gagnon JA, Lord ND, Rogers KW, Mosimann C, Zon LI, Schier AF. Norris ML, et al. Among authors: gagnon ja. Elife. 2017 Nov 9;6:e22626. doi: 10.7554/eLife.22626. Elife. 2017. PMID: 29117894 Free PMC article.

9

The primary role of zebrafish nanog is in extra-embryonic tissue.

Gagnon JA, Obbad K, Schier AF. Gagnon JA, et al. Development. 2018 Jan 9;145(1):dev147793. doi: 10.1242/dev.147793. Development. 2018. PMID: 29180571 Free PMC article.

10

Nodal patterning without Lefty inhibitory feedback is functional but fragile.

Rogers KW, Lord ND, Gagnon JA, Pauli A, Zimmerman S, Aksel DC, Reyon D, Tsai SQ, Joung JK, Schier AF. Rogers KW, et al. Among authors: gagnon ja. Elife. 2017 Dec 7;6:e28785. doi: 10.7554/eLife.28785. Elife. 2017. PMID: 29215332 Free PMC article.

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