Shingu T - Search Results

1

Utilizing murine inducible telomerase alleles in the studies of tissue degeneration/regeneration and cancer.

Shingu T, Jaskelioff M, Yuan L, Ding Z, Protopopov A, Kost-Alimova M, Hu J. Shingu T, et al. J Vis Exp. 2015 Apr 13;(98):52599. doi: 10.3791/52599. J Vis Exp. 2015. PMID: 25938254 Free PMC article.

2

Qki deficiency maintains stemness of glioma stem cells in suboptimal environment by downregulating endolysosomal degradation.

Shingu T, Ho AL, Yuan L, Zhou X, Dai C, Zheng S, Wang Q, Zhong Y, Chang Q, Horner JW, Liebelt BD, Yao Y, Hu B, Chen Y, Fuller GN, Verhaak RG, Heimberger AB, Hu J. Shingu T, et al. Nat Genet. 2017 Jan;49(1):75-86. doi: 10.1038/ng.3711. Epub 2016 Nov 14. Nat Genet. 2017. PMID: 27841882 Free PMC article.

3

Qki is an essential regulator of microglial phagocytosis in demyelination.

Ren J, Dai C, Zhou X, Barnes JA, Chen X, Wang Y, Yuan L, Shingu T, Heimberger AB, Chen Y, Hu J. Ren J, et al. Among authors: shingu t. J Exp Med. 2021 Jan 4;218(1):e20190348. doi: 10.1084/jem.20190348. J Exp Med. 2021. PMID: 33045062 Free PMC article.

4

Glioma Stem Cells: Signaling, Microenvironment, and Therapy.

Liebelt BD, Shingu T, Zhou X, Ren J, Shin SA, Hu J. Liebelt BD, et al. Among authors: shingu t. Stem Cells Int. 2016;2016:7849890. doi: 10.1155/2016/7849890. Epub 2016 Jan 6. Stem Cells Int. 2016. PMID: 26880988 Free PMC article. Review.

5

Qki regulates myelinogenesis through Srebp2-dependent cholesterol biosynthesis.

Zhou X, Shin S, He C, Zhang Q, Rasband MN, Ren J, Dai C, Zorrilla-Veloz RI, Shingu T, Yuan L, Wang Y, Chen Y, Lan F, Hu J. Zhou X, et al. Among authors: shingu t. Elife. 2021 May 4;10:e60467. doi: 10.7554/eLife.60467. Elife. 2021. PMID: 33942715 Free PMC article.

6

Suppression of RAF/MEK or PI3K synergizes cytotoxicity of receptor tyrosine kinase inhibitors in glioma tumor-initiating cells.

Shingu T, Holmes L, Henry V, Wang Q, Latha K, Gururaj AE, Gibson LA, Doucette T, Lang FF, Rao G, Yuan L, Sulman EP, Farrell NP, Priebe W, Hess KR, Wang YA, Hu J, Bögler O. Shingu T, et al. J Transl Med. 2016 Feb 9;14:46. doi: 10.1186/s12967-016-0803-2. J Transl Med. 2016. PMID: 26861698 Free PMC article.

7

Quaking but not parkin is the major tumor suppressor in 6q deleted region in glioblastoma.

Aksoy Yasar FB, Shingu T, Zamler DB, Zaman MF, Chien DL, Zhang Q, Ren J, Hu J. Aksoy Yasar FB, et al. Among authors: shingu t. Front Cell Dev Biol. 2022 Aug 16;10:931387. doi: 10.3389/fcell.2022.931387. eCollection 2022. Front Cell Dev Biol. 2022. PMID: 36051438 Free PMC article.

8

Mature myelin maintenance requires Qki to coactivate PPARβ-RXRα-mediated lipid metabolism.

Zhou X, He C, Ren J, Dai C, Stevens SR, Wang Q, Zamler D, Shingu T, Yuan L, Chandregowda CR, Wang Y, Ravikumar V, Rao AU, Zhou F, Zheng H, Rasband MN, Chen Y, Lan F, Heimberger AB, Segal BM, Hu J. Zhou X, et al. Among authors: shingu t. J Clin Invest. 2020 May 1;130(5):2220-2236. doi: 10.1172/JCI131800. J Clin Invest. 2020. PMID: 32202512 Free PMC article.

9

Qki activates Srebp2-mediated cholesterol biosynthesis for maintenance of eye lens transparency.

Shin S, Zhou H, He C, Wei Y, Wang Y, Shingu T, Zeng A, Wang S, Zhou X, Li H, Zhang Q, Mo Q, Long J, Lan F, Chen Y, Hu J. Shin S, et al. Among authors: shingu t. Nat Commun. 2021 May 21;12(1):3005. doi: 10.1038/s41467-021-22782-0. Nat Commun. 2021. PMID: 34021134 Free PMC article.

10

Immune landscape of a genetically engineered murine model of glioma compared with human glioma.

Zamler DB, Shingu T, Kahn LM, Huntoon K, Kassab C, Ott M, Tomczak K, Liu J, Li Y, Lai I, Zorilla-Veloz R, Yee C, Rai K, Kim BY, Watowich SS, Heimberger AB, Draetta GF, Hu J. Zamler DB, et al. Among authors: shingu t. JCI Insight. 2022 Jun 22;7(12):e148990. doi: 10.1172/jci.insight.148990. JCI Insight. 2022. PMID: 35653194 Free PMC article.

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