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Myosin light chain kinase expression induced via tumor necrosis factor receptor 2 signaling in the epithelial cells regulates the development of colitis-associated carcinogenesis.
Suzuki M, Nagaishi T, Yamazaki M, Onizawa M, Watabe T, Sakamaki Y, Ichinose S, Totsuka M, Oshima S, Okamoto R, Shimonaka M, Yagita H, Nakamura T, Watanabe M. Suzuki M, et al. Among authors: onizawa m. PLoS One. 2014 Feb 10;9(2):e88369. doi: 10.1371/journal.pone.0088369. eCollection 2014. PLoS One. 2014. PMID: 24520376 Free PMC article.
Erratum: The ubiquitin-modifying enzyme A20 restricts ubiquitination of the kinase RIPK3 and protects cells from necroptosis.
Onizawa M, Oshima S, Schulze-Topphoff U, Oses-Prieto JA, Lu T, Tavares R, Prodhomme T, Duong B, Whang MI, Advincula R, Agelidis A, Barrera J, Wu H, Burlingame A, Malynn BA, Zamvil SS, Ma A. Onizawa M, et al. Nat Immunol. 2015 Jul;16(7):785. doi: 10.1038/ni0715-785c. Nat Immunol. 2015. PMID: 26086145 Free PMC article. No abstract available.
A20 and ABIN-1 synergistically preserve intestinal epithelial cell survival.
Kattah MG, Shao L, Rosli YY, Shimizu H, Whang MI, Advincula R, Achacoso P, Shah S, Duong BH, Onizawa M, Tanbun P, Malynn BA, Ma A. Kattah MG, et al. Among authors: onizawa m. J Exp Med. 2018 Jul 2;215(7):1839-1852. doi: 10.1084/jem.20180198. Epub 2018 Jun 21. J Exp Med. 2018. PMID: 29930103 Free PMC article.
Receptor-Interacting Protein Kinase 3 (RIPK3) inhibits autophagic flux during necroptosis in intestinal epithelial cells.
Otsubo K, Maeyashiki C, Nibe Y, Tamura A, Aonuma E, Matsuda H, Kobayashi M, Onizawa M, Nemoto Y, Nagaishi T, Okamoto R, Tsuchiya K, Nakamura T, Torii S, Itakura E, Watanabe M, Oshima S. Otsubo K, et al. Among authors: onizawa m. FEBS Lett. 2020 May;594(10):1586-1595. doi: 10.1002/1873-3468.13748. Epub 2020 Feb 16. FEBS Lett. 2020. PMID: 31997355 Free article.
Signaling pathway via TNF-alpha/NF-kappaB in intestinal epithelial cells may be directly involved in colitis-associated carcinogenesis.
Onizawa M, Nagaishi T, Kanai T, Nagano K, Oshima S, Nemoto Y, Yoshioka A, Totsuka T, Okamoto R, Nakamura T, Sakamoto N, Tsuchiya K, Aoki K, Ohya K, Yagita H, Watanabe M. Onizawa M, et al. Am J Physiol Gastrointest Liver Physiol. 2009 Apr;296(4):G850-9. doi: 10.1152/ajpgi.00071.2008. Epub 2009 Jan 29. Am J Physiol Gastrointest Liver Physiol. 2009. PMID: 19179628 Free article.
42 results