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Page 1
Concise and Practical Asymmetric Synthesis of a Challenging Atropisomeric HIV Integrase Inhibitor.
Fandrick KR, Li W, Zhang Y, Tang W, Gao J, Rodriguez S, Patel ND, Reeves DC, Wu JP, Sanyal S, Gonnella N, Qu B, Haddad N, Lorenz JC, Sidhu K, Wang J, Ma S, Grinberg N, Lee H, Tsantrizos Y, Poupart MA, Busacca CA, Yee NK, Lu BZ, Senanayake CH. Fandrick KR, et al. Among authors: haddad n. Angew Chem Int Ed Engl. 2015 Jun 8;54(24):7144-8. doi: 10.1002/anie.201501575. Epub 2015 May 4. Angew Chem Int Ed Engl. 2015. PMID: 25939331
Large-scale asymmetric synthesis of a cathepsin S inhibitor.
Lorenz JC, Busacca CA, Feng X, Grinberg N, Haddad N, Johnson J, Kapadia S, Lee H, Saha A, Sarvestani M, Spinelli EM, Varsolona R, Wei X, Zeng X, Senanayake CH. Lorenz JC, et al. Among authors: haddad n. J Org Chem. 2010 Feb 19;75(4):1155-61. doi: 10.1021/jo9022809. J Org Chem. 2010. PMID: 20102230
A general and special catalyst for Suzuki-Miyaura coupling processes.
Tang W, Capacci AG, Wei X, Li W, White A, Patel ND, Savoie J, Gao JJ, Rodriguez S, Qu B, Haddad N, Lu BZ, Krishnamurthy D, Yee NK, Senanayake CH. Tang W, et al. Among authors: haddad n. Angew Chem Int Ed Engl. 2010 Aug 9;49(34):5879-83. doi: 10.1002/anie.201002404. Angew Chem Int Ed Engl. 2010. PMID: 20632427 No abstract available.
Remarkable enhancement of enantioselectivity in the asymmetric conjugate addition of dimethylzinc to (Z)-nitroalkenes with a catalytic [(MeCN)₄Cu]PF₆-Hoveyda ligand complex.
Zeng X, Gao JJ, Song JJ, Ma S, Desrosiers JN, Mulder JA, Rodriguez S, Herbage MA, Haddad N, Qu B, Fandrick KR, Grinberg N, Lee H, Wei X, Yee NK, Senanayake CH. Zeng X, et al. Among authors: haddad n. Angew Chem Int Ed Engl. 2014 Nov 3;53(45):12153-7. doi: 10.1002/anie.201406247. Epub 2014 Sep 15. Angew Chem Int Ed Engl. 2014. PMID: 25225113
A mild dihydrobenzooxaphosphole oxazoline/iridium catalytic system for asymmetric hydrogenation of unfunctionalized dialins.
Qu B, Samankumara LP, Ma S, Fandrick KR, Desrosiers JN, Rodriguez S, Li Z, Haddad N, Han ZS, McKellop K, Pennino S, Grinberg N, Gonnella NC, Song JJ, Senanayake CH. Qu B, et al. Among authors: haddad n. Angew Chem Int Ed Engl. 2014 Dec 22;53(52):14428-32. doi: 10.1002/anie.201408929. Epub 2014 Nov 10. Angew Chem Int Ed Engl. 2014. PMID: 25385009
Sequential C-H Arylation and Enantioselective Hydrogenation Enables Ideal Asymmetric Entry to the Indenopiperidine Core of an 11β-HSD-1 Inhibitor.
Wei X, Qu B, Zeng X, Savoie J, Fandrick KR, Desrosiers JN, Tcyrulnikov S, Marsini MA, Buono FG, Li Z, Yang BS, Tang W, Haddad N, Gutierrez O, Wang J, Lee H, Ma S, Campbell S, Lorenz JC, Eckhardt M, Himmelsbach F, Peters S, Patel ND, Tan Z, Yee NK, Song JJ, Roschangar F, Kozlowski MC, Senanayake CH. Wei X, et al. Among authors: haddad n. J Am Chem Soc. 2016 Nov 30;138(47):15473-15481. doi: 10.1021/jacs.6b09764. Epub 2016 Nov 17. J Am Chem Soc. 2016. PMID: 27794616 Free PMC article.
Asymmetric hydrogenation of unsaturated ureas with the BIPI ligands.
Busacca CA, Lorenz JC, Grinberg N, Haddad N, Lee H, Li Z, Liang M, Reeves D, Saha A, Varsolona R, Senanayake CH. Busacca CA, et al. Among authors: haddad n. Org Lett. 2008 Jan 17;10(2):341-4. doi: 10.1021/ol7028542. Epub 2007 Dec 21. Org Lett. 2008. PMID: 18095698
982 results