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Page 1
Concise and Practical Asymmetric Synthesis of a Challenging Atropisomeric HIV Integrase Inhibitor.
Fandrick KR, Li W, Zhang Y, Tang W, Gao J, Rodriguez S, Patel ND, Reeves DC, Wu JP, Sanyal S, Gonnella N, Qu B, Haddad N, Lorenz JC, Sidhu K, Wang J, Ma S, Grinberg N, Lee H, Tsantrizos Y, Poupart MA, Busacca CA, Yee NK, Lu BZ, Senanayake CH. Fandrick KR, et al. Among authors: wu jp. Angew Chem Int Ed Engl. 2015 Jun 8;54(24):7144-8. doi: 10.1002/anie.201501575. Epub 2015 May 4. Angew Chem Int Ed Engl. 2015. PMID: 25939331
[2,3]-Sigmatropic rearrangements of 2-phosphineborane 2-propen-1-ols: rapid access to enantioenriched diphosphine monoxide derivatives.
Busacca CA, Qu B, Farber E, Haddad N, Grět N, Saha AK, Eriksson MC, Wu JP, Fandrick KR, Han S, Grinberg N, Ma S, Lee H, Li Z, Spinelli M, Gold A, Wang Z, Wang G, Wipf P, Senanayake CH. Busacca CA, et al. Among authors: wu jp. Org Lett. 2013 Mar 1;15(5):1136-9. doi: 10.1021/ol400310h. Epub 2013 Feb 21. Org Lett. 2013. PMID: 23427861
Hydrophosphination of propargylic alcohols and amines with phosphine boranes.
Busacca CA, Qu B, Farber E, Haddad N, Grět N, Saha AK, Eriksson MC, Wu JP, Fandrick KR, Han S, Grinberg N, Ma S, Lee H, Li Z, Spinelli M, Gold A, Wang G, Wipf P, Senanayake CH. Busacca CA, et al. Among authors: wu jp. Org Lett. 2013 Mar 1;15(5):1132-5. doi: 10.1021/ol400309y. Epub 2013 Feb 21. Org Lett. 2013. PMID: 23427869
Structure Elucidation of Poly-Faldaprevir: Polymer Backbone Solved Using Solid-State and Solution Nuclear Magnetic Resonance Spectroscopy.
Gonnella NC, Busacca CA, Zhang L, Saha A, Wu JP, Li G, Davis M, Offerdahl T, Jones PJ, Herfurth L, Reddig T, Wagner K, Niemann M, Werthmann U, Grupe J, Roos H, Reckzügel G, Ding A. Gonnella NC, et al. Among authors: wu jp. J Pharm Sci. 2016 Jun;105(6):1881-1890. doi: 10.1016/j.xphs.2016.03.017. J Pharm Sci. 2016. PMID: 27238486
Pyrazinoindolone inhibitors of MAPKAP-K2.
Goldberg DR, Choi Y, Cogan D, Corson M, DeLeon R, Gao A, Gruenbaum L, Hao MH, Joseph D, Kashem MA, Miller C, Moss N, Netherton MR, Pargellis CP, Pelletier J, Sellati R, Skow D, Torcellini C, Tseng YC, Wang J, Wasti R, Werneburg B, Wu JP, Xiong Z. Goldberg DR, et al. Among authors: wu jp. Bioorg Med Chem Lett. 2008 Feb 1;18(3):938-41. doi: 10.1016/j.bmcl.2007.12.037. Epub 2007 Dec 23. Bioorg Med Chem Lett. 2008. PMID: 18221871
Evolution of the thienopyridine class of inhibitors of IkappaB kinase-beta: part I: hit-to-lead strategies.
Morwick T, Berry A, Brickwood J, Cardozo M, Catron K, DeTuri M, Emeigh J, Homon C, Hrapchak M, Jacober S, Jakes S, Kaplita P, Kelly TA, Ksiazek J, Liuzzi M, Magolda R, Mao C, Marshall D, McNeil D, Prokopowicz A 3rd, Sarko C, Scouten E, Sledziona C, Sun S, Watrous J, Wu JP, Cywin CL. Morwick T, et al. Among authors: wu jp. J Med Chem. 2006 May 18;49(10):2898-908. doi: 10.1021/jm0510979. J Med Chem. 2006. PMID: 16686533
The discovery of thienopyridine analogues as potent IkappaB kinase beta inhibitors. Part II.
Wu JP, Fleck R, Brickwood J, Capolino A, Catron K, Chen Z, Cywin C, Emeigh J, Foerst M, Ginn J, Hrapchak M, Hickey E, Hao MH, Kashem M, Li J, Liu W, Morwick T, Nelson R, Marshall D, Martin L, Nemoto P, Potocki I, Liuzzi M, Peet GW, Scouten E, Stefany D, Turner M, Weldon S, Zimmitti C, Spero D, Kelly TA. Wu JP, et al. Bioorg Med Chem Lett. 2009 Oct 1;19(19):5547-51. doi: 10.1016/j.bmcl.2009.08.054. Epub 2009 Aug 15. Bioorg Med Chem Lett. 2009. PMID: 19716697
Second-generation lymphocyte function-associated antigen-1 inhibitors: 1H-imidazo[1,2-alpha]imidazol-2-one derivatives.
Wu JP, Emeigh J, Gao DA, Goldberg DR, Kuzmich D, Miao C, Potocki I, Qian KC, Sorcek RJ, Jeanfavre DD, Kishimoto K, Mainolfi EA, Nabozny G Jr, Peng C, Reilly P, Rothlein R, Sellati RH, Woska JR Jr, Chen S, Gunn JA, O'Brien D, Norris SH, Kelly TA. Wu JP, et al. J Med Chem. 2004 Oct 21;47(22):5356-66. doi: 10.1021/jm049657b. J Med Chem. 2004. PMID: 15481974
N-Arylsulfonyl-α-amino carboxamides are potent and selective inhibitors of the chemokine receptor CCR10 that show efficacy in the murine DNFB model of contact hypersensitivity.
Abeywardane A, Caviness G, Choi Y, Cogan D, Gao A, Goldberg D, Heim-Riether A, Jeanfavre D, Klein E, Kowalski JA, Mao W, Miller C, Moss N, Ramsden P, Raymond E, Skow D, Smith-Keenan L, Snow RJ, Wu F, Wu JP, Yu Y. Abeywardane A, et al. Among authors: wu f, wu jp. Bioorg Med Chem Lett. 2016 Nov 1;26(21):5277-5283. doi: 10.1016/j.bmcl.2016.09.047. Epub 2016 Sep 21. Bioorg Med Chem Lett. 2016. PMID: 27692854 Free article.
442 results