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Page 1
Genomic landscape of rat strain and substrain variation.
Hermsen R, de Ligt J, Spee W, Blokzijl F, Schäfer S, Adami E, Boymans S, Flink S, van Boxtel R, van der Weide RH, Aitman T, Hübner N, Simonis M, Tabakoff B, Guryev V, Cuppen E. Hermsen R, et al. Among authors: boymans s. BMC Genomics. 2015 May 6;16(1):357. doi: 10.1186/s12864-015-1594-1. BMC Genomics. 2015. PMID: 25943489 Free PMC article.
Genomic and functional overlap between somatic and germline chromosomal rearrangements.
van Heesch S, Simonis M, van Roosmalen MJ, Pillalamarri V, Brand H, Kuijk EW, de Luca KL, Lansu N, Braat AK, Menelaou A, Hao W, Korving J, Snijder S, van der Veken LT, Hochstenbach R, Knegt AC, Duran K, Renkens I, Alekozai N, Jager M, Vergult S, Menten B, de Bruijn E, Boymans S, Ippel E, van Binsbergen E, Talkowski ME, Lichtenbelt K, Cuppen E, Kloosterman WP. van Heesch S, et al. Among authors: boymans s. Cell Rep. 2014 Dec 24;9(6):2001-10. doi: 10.1016/j.celrep.2014.11.022. Epub 2014 Dec 11. Cell Rep. 2014. PMID: 25497101 Free article.
Tissue-specific mutation accumulation in human adult stem cells during life.
Blokzijl F, de Ligt J, Jager M, Sasselli V, Roerink S, Sasaki N, Huch M, Boymans S, Kuijk E, Prins P, Nijman IJ, Martincorena I, Mokry M, Wiegerinck CL, Middendorp S, Sato T, Schwank G, Nieuwenhuis EE, Verstegen MM, van der Laan LJ, de Jonge J, IJzermans JN, Vries RG, van de Wetering M, Stratton MR, Clevers H, Cuppen E, van Boxtel R. Blokzijl F, et al. Among authors: boymans s. Nature. 2016 Oct 13;538(7624):260-264. doi: 10.1038/nature19768. Epub 2016 Oct 3. Nature. 2016. PMID: 27698416 Free PMC article.
Early divergence of mutational processes in human fetal tissues.
Kuijk E, Blokzijl F, Jager M, Besselink N, Boymans S, Chuva de Sousa Lopes SM, van Boxtel R, Cuppen E. Kuijk E, et al. Among authors: boymans s. Sci Adv. 2019 May 29;5(5):eaaw1271. doi: 10.1126/sciadv.aaw1271. eCollection 2019 May. Sci Adv. 2019. PMID: 31149636 Free PMC article.
5-Fluorouracil treatment induces characteristic T>G mutations in human cancer.
Christensen S, Van der Roest B, Besselink N, Janssen R, Boymans S, Martens JWM, Yaspo ML, Priestley P, Kuijk E, Cuppen E, Van Hoeck A. Christensen S, et al. Among authors: boymans s. Nat Commun. 2019 Oct 8;10(1):4571. doi: 10.1038/s41467-019-12594-8. Nat Commun. 2019. PMID: 31594944 Free PMC article.
Prioritization of genes driving congenital phenotypes of patients with de novo genomic structural variants.
Middelkamp S, Vlaar JM, Giltay J, Korzelius J, Besselink N, Boymans S, Janssen R, de la Fonteijne L, van Binsbergen E, van Roosmalen MJ, Hochstenbach R, Giachino D, Talkowski ME, Kloosterman WP, Cuppen E. Middelkamp S, et al. Among authors: boymans s. Genome Med. 2019 Dec 4;11(1):79. doi: 10.1186/s13073-019-0692-0. Genome Med. 2019. PMID: 31801603 Free PMC article.
The mutational impact of culturing human pluripotent and adult stem cells.
Kuijk E, Jager M, van der Roest B, Locati MD, Van Hoeck A, Korzelius J, Janssen R, Besselink N, Boymans S, van Boxtel R, Cuppen E. Kuijk E, et al. Among authors: boymans s. Nat Commun. 2020 May 19;11(1):2493. doi: 10.1038/s41467-020-16323-4. Nat Commun. 2020. PMID: 32427826 Free PMC article.
18 results