Miyoshi H - Search Results

1

Ascosteroside C, a new mitochondrial respiration inhibitor discovered by pesticidal screening using recombinant Saccharomyces cerevisiae.

Suga T, Asami Y, Hashimoto S, Nonaka K, Iwatsuki M, Nakashima T, Sugahara R, Shiotsuki T, Yamamoto T, Shinohara Y, Ichimaru N, Murai M, Miyoshi H, Ōmura S, Shiomi K. Suga T, et al. Among authors: miyoshi h. J Antibiot (Tokyo). 2015 Oct;68(10):649-52. doi: 10.1038/ja.2015.43. Epub 2015 May 6. J Antibiot (Tokyo). 2015. PMID: 25944534 No abstract available.

2

An anthelmintic compound, nafuredin, shows selective inhibition of complex I in helminth mitochondria.

Omura S, Miyadera H, Ui H, Shiomi K, Yamaguchi Y, Masuma R, Nagamitsu T, Takano D, Sunazuka T, Harder A, Kölbl H, Namikoshi M, Miyoshi H, Sakamoto K, Kita K. Omura S, et al. Among authors: miyoshi h. Proc Natl Acad Sci U S A. 2001 Jan 2;98(1):60-2. doi: 10.1073/pnas.98.1.60. Proc Natl Acad Sci U S A. 2001. PMID: 11120889 Free PMC article.

3

Atpenins, potent and specific inhibitors of mitochondrial complex II (succinate-ubiquinone oxidoreductase).

Miyadera H, Shiomi K, Ui H, Yamaguchi Y, Masuma R, Tomoda H, Miyoshi H, Osanai A, Kita K, Omura S. Miyadera H, et al. Among authors: miyoshi h. Proc Natl Acad Sci U S A. 2003 Jan 21;100(2):473-7. doi: 10.1073/pnas.0237315100. Epub 2003 Jan 6. Proc Natl Acad Sci U S A. 2003. PMID: 12515859 Free PMC article.

4

Essential structural features of acetogenins: role of hydroxy groups adjacent to the bis-THF rings.

Abe M, Kenmochi A, Ichimaru N, Hamada T, Nishioka T, Miyoshi H. Abe M, et al. Among authors: miyoshi h. Bioorg Med Chem Lett. 2004 Feb 9;14(3):779-82. doi: 10.1016/j.bmcl.2003.11.021. Bioorg Med Chem Lett. 2004. PMID: 14741288

5

Synthesis and inhibitory action of novel acetogenin mimics with bovine heart mitochondrial complex I.

Hamada T, Ichimaru N, Abe M, Fujita D, Kenmochi A, Nishioka T, Zwicker K, Brandt U, Miyoshi H. Hamada T, et al. Among authors: miyoshi h. Biochemistry. 2004 Mar 30;43(12):3651-8. doi: 10.1021/bi030242m. Biochemistry. 2004. PMID: 15035635

6

Synthesis and inhibition mechanism of Delta lac-acetogenins, a novel type of inhibitor of bovine heart mitochondrial complex I.

Ichimaru N, Murai M, Abe M, Hamada T, Yamada Y, Makino S, Nishioka T, Makabe H, Makino A, Kobayashi T, Miyoshi H. Ichimaru N, et al. Among authors: miyoshi h. Biochemistry. 2005 Jan 18;44(2):816-25. doi: 10.1021/bi0479003. Biochemistry. 2005. PMID: 15641810

7

A gamma-lactone form nafuredin, nafuredin-gamma, also inhibits helminth complex I.

Shiomi K, Ui H, Suzuki H, Hatano H, Nagamitsu T, Takano D, Miyadera H, Yamashita T, Kita K, Miyoshi H, Harder A, Tomoda H, Omura S. Shiomi K, et al. Among authors: miyoshi h. J Antibiot (Tokyo). 2005 Jan;58(1):50-5. doi: 10.1038/ja.2005.5. J Antibiot (Tokyo). 2005. PMID: 15813180

8

Dynamic function of the alkyl spacer of acetogenins in their inhibitory action with mitochondrial complex I (NADH-ubiquinone oxidoreductase).

Abe M, Murai M, Ichimaru N, Kenmochi A, Yoshida T, Kubo A, Kimura Y, Moroda A, Makabe H, Nishioka T, Miyoshi H. Abe M, et al. Among authors: miyoshi h. Biochemistry. 2005 Nov 15;44(45):14898-906. doi: 10.1021/bi051568t. Biochemistry. 2005. PMID: 16274237

9

Synthesis of (4R,15R,16R,21S)- and (4R,15S,16S,21S)-rollicosin, squamostolide, and their inhibitory action with bovine heart mitochondrial complex I.

Makabe H, Kimura Y, Higuchi M, Konno H, Murai M, Miyoshi H. Makabe H, et al. Among authors: miyoshi h. Bioorg Med Chem. 2006 May 1;14(9):3119-30. doi: 10.1016/j.bmc.2005.12.015. Epub 2006 Jan 23. Bioorg Med Chem. 2006. PMID: 16431114

10

Function of the alkyl side chains of Deltalac-acetogenins in the inhibitory effect on mitochondrial complex I (NADH-ubiquinone oxidoreductase).

Ichimaru N, Abe M, Murai M, Senoh M, Nishioka T, Miyoshi H. Ichimaru N, et al. Among authors: miyoshi h. Bioorg Med Chem Lett. 2006 Jul 1;16(13):3555-8. doi: 10.1016/j.bmcl.2006.03.082. Epub 2006 Apr 18. Bioorg Med Chem Lett. 2006. PMID: 16621539

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