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IWGT report on quantitative approaches to genotoxicity risk assessment I. Methods and metrics for defining exposure-response relationships and points of departure (PoDs).
MacGregor JT, Frötschl R, White PA, Crump KS, Eastmond DA, Fukushima S, Guérard M, Hayashi M, Soeteman-Hernández LG, Kasamatsu T, Levy DD, Morita T, Müller L, Schoeny R, Schuler MJ, Thybaud V, Johnson GE. MacGregor JT, et al. Among authors: fukushima s. Mutat Res Genet Toxicol Environ Mutagen. 2015 May 1;783:55-65. doi: 10.1016/j.mrgentox.2014.09.011. Epub 2014 Oct 13. Mutat Res Genet Toxicol Environ Mutagen. 2015. PMID: 25953400 Free article.
IWGT report on quantitative approaches to genotoxicity risk assessment II. Use of point-of-departure (PoD) metrics in defining acceptable exposure limits and assessing human risk.
MacGregor JT, Frötschl R, White PA, Crump KS, Eastmond DA, Fukushima S, Guérard M, Hayashi M, Soeteman-Hernández LG, Johnson GE, Kasamatsu T, Levy DD, Morita T, Müller L, Schoeny R, Schuler MJ, Thybaud V. MacGregor JT, et al. Among authors: fukushima s. Mutat Res Genet Toxicol Environ Mutagen. 2015 May 1;783:66-78. doi: 10.1016/j.mrgentox.2014.10.008. Epub 2014 Oct 27. Mutat Res Genet Toxicol Environ Mutagen. 2015. PMID: 25953401 Free article.
The safety evaluation of food flavoring substances: the role of genotoxicity studies.
Gooderham NJ, Cohen SM, Eisenbrand G, Fukushima S, Guengerich FP, Hecht SS, Rietjens IMCM, Rosol TJ, Bastaki M, Linman MJ, Taylor SV. Gooderham NJ, et al. Among authors: fukushima s. Crit Rev Toxicol. 2020 Jan;50(1):1-27. doi: 10.1080/10408444.2020.1712589. Epub 2020 Mar 12. Crit Rev Toxicol. 2020. PMID: 32162576 Free article. Review.
Impact of structural and metabolic variations on the toxicity and carcinogenicity of hydroxy- and alkoxy-substituted allyl- and propenylbenzenes.
Rietjens IM, Cohen SM, Fukushima S, Gooderham NJ, Hecht S, Marnett LJ, Smith RL, Adams TB, Bastaki M, Harman CG, Taylor SV. Rietjens IM, et al. Among authors: fukushima s. Chem Res Toxicol. 2014 Jul 21;27(7):1092-103. doi: 10.1021/tx500109s. Epub 2014 Jun 11. Chem Res Toxicol. 2014. PMID: 24857813 Free article.
Safety evaluation of substituted thiophenes used as flavoring ingredients.
Cohen SM, Fukushima S, Gooderham NJ, Guengerich FP, Hecht SS, Rietjens IM, Smith RL, Bastaki M, Harman CL, McGowen MM, Valerio LG, Taylor SV. Cohen SM, et al. Among authors: fukushima s. Food Chem Toxicol. 2017 Jan;99:40-59. doi: 10.1016/j.fct.2016.10.023. Epub 2016 Nov 9. Food Chem Toxicol. 2017. PMID: 27836750 Free article. Review.
FEMA expert panel review of p-mentha-1,8-dien-7-al genotoxicity testing results.
Cohen SM, Fukushima S, Gooderham NJ, Guengerich FP, Hecht SS, Rietjens IMCM, Smith RL, Bastaki M, Harman CL, McGowen MM, Taylor SV. Cohen SM, et al. Among authors: fukushima s. Food Chem Toxicol. 2016 Dec;98(Pt B):201-209. doi: 10.1016/j.fct.2016.10.020. Epub 2016 Oct 20. Food Chem Toxicol. 2016. PMID: 27773699 Free article. Review.
The safety evaluation of food flavouring substances: the role of metabolic studies.
Smith RL, Cohen SM, Fukushima S, Gooderham NJ, Hecht SS, Guengerich FP, Rietjens IMCM, Bastaki M, Harman CL, McGowen MM, Taylor SV. Smith RL, et al. Among authors: fukushima s. Toxicol Res (Camb). 2018 Mar 28;7(4):618-646. doi: 10.1039/c7tx00254h. eCollection 2018 Jul 1. Toxicol Res (Camb). 2018. PMID: 30090611 Free PMC article. Review.
FEMA GRAS assessment of natural flavor complexes: Origanum oil, thyme oil and related phenol derivative-containing flavoring ingredients.
Cohen SM, Eisenbrand G, Fukushima S, Gooderham NJ, Guengerich FP, Hecht SS, Rietjens IMCM, Rosol TJ, Davidsen JM, Harman CL, Lu V, Taylor SV. Cohen SM, et al. Among authors: fukushima s. Food Chem Toxicol. 2021 Sep;155:112378. doi: 10.1016/j.fct.2021.112378. Epub 2021 Jul 1. Food Chem Toxicol. 2021. PMID: 34217738 Free article.
2,201 results