Dooley S - Search Results

1

Hepatocyte fate upon TGF-β challenge is determined by the matrix environment.

Meyer C, Liebe R, Breitkopf-Heinlein K, Liu Y, Müller A, Rakoczy P, Thomas M, Weng H, Bachmann A, Ebert M, Dooley S. Meyer C, et al. Among authors: dooley s. Differentiation. 2015 Jun;89(5):105-16. doi: 10.1016/j.diff.2015.04.001. Epub 2015 May 14. Differentiation. 2015. PMID: 25982745

2

Y-box protein-1 is the crucial mediator of antifibrotic interferon-gamma effects.

Dooley S, Said HM, Gressner AM, Floege J, En-Nia A, Mertens PR. Dooley S, et al. J Biol Chem. 2006 Jan 20;281(3):1784-95. doi: 10.1074/jbc.M510215200. Epub 2005 Nov 8. J Biol Chem. 2006. PMID: 16278212 Free article.

3

Anti-TGF-beta strategies for the treatment of chronic liver disease.

Breitkopf K, Haas S, Wiercinska E, Singer MV, Dooley S. Breitkopf K, et al. Among authors: dooley s. Alcohol Clin Exp Res. 2005 Nov;29(11 Suppl):121S-131S. doi: 10.1097/01.alc.0000189284.98684.22. Alcohol Clin Exp Res. 2005. PMID: 16344596 Review.

4

TGF-beta/Smad signaling in the injured liver.

Breitkopf K, Godoy P, Ciuclan L, Singer MV, Dooley S. Breitkopf K, et al. Among authors: dooley s. Z Gastroenterol. 2006 Jan;44(1):57-66. doi: 10.1055/s-2005-858989. Z Gastroenterol. 2006. PMID: 16397841 Review.

5

IFN-gamma abrogates profibrogenic TGF-beta signaling in liver by targeting expression of inhibitory and receptor Smads.

Weng H, Mertens PR, Gressner AM, Dooley S. Weng H, et al. Among authors: dooley s. J Hepatol. 2007 Feb;46(2):295-303. doi: 10.1016/j.jhep.2006.09.014. Epub 2006 Nov 3. J Hepatol. 2007. PMID: 17125875

6

Profibrogenic transforming growth factor-beta/activin receptor-like kinase 5 signaling via connective tissue growth factor expression in hepatocytes.

Weng HL, Ciuclan L, Liu Y, Hamzavi J, Godoy P, Gaitantzi H, Kanzler S, Heuchel R, Ueberham U, Gebhardt R, Breitkopf K, Dooley S. Weng HL, et al. Among authors: dooley s. Hepatology. 2007 Oct;46(4):1257-70. doi: 10.1002/hep.21806. Hepatology. 2007. PMID: 17657819

7

Disruption of the Smad7 gene enhances CCI4-dependent liver damage and fibrogenesis in mice.

Hamzavi J, Ehnert S, Godoy P, Ciuclan L, Weng H, Mertens PR, Heuchel R, Dooley S. Hamzavi J, et al. Among authors: dooley s. J Cell Mol Med. 2008 Oct;12(5B):2130-44. doi: 10.1111/j.1582-4934.2008.00262.x. Epub 2008 Feb 4. J Cell Mol Med. 2008. PMID: 18266971 Free PMC article.

8

Transforming growth factor-beta and hepatocyte transdifferentiation in liver fibrogenesis.

Meindl-Beinker NM, Dooley S. Meindl-Beinker NM, et al. Among authors: dooley s. J Gastroenterol Hepatol. 2008 Mar;23 Suppl 1:S122-7. doi: 10.1111/j.1440-1746.2007.05297.x. J Gastroenterol Hepatol. 2008. PMID: 18336655

9

Hepatocyte-specific Smad7 expression attenuates TGF-beta-mediated fibrogenesis and protects against liver damage.

Dooley S, Hamzavi J, Ciuclan L, Godoy P, Ilkavets I, Ehnert S, Ueberham E, Gebhardt R, Kanzler S, Geier A, Breitkopf K, Weng H, Mertens PR. Dooley S, et al. Gastroenterology. 2008 Aug;135(2):642-59. doi: 10.1053/j.gastro.2008.04.038. Epub 2008 May 15. Gastroenterology. 2008. PMID: 18602923 Free article.

10

Extracellular matrix modulates sensitivity of hepatocytes to fibroblastoid dedifferentiation and transforming growth factor beta-induced apoptosis.

Godoy P, Hengstler JG, Ilkavets I, Meyer C, Bachmann A, Müller A, Tuschl G, Mueller SO, Dooley S. Godoy P, et al. Among authors: dooley s. Hepatology. 2009 Jun;49(6):2031-43. doi: 10.1002/hep.22880. Hepatology. 2009. PMID: 19274752

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