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Non-genotoxic carcinogen exposure induces defined changes in the 5-hydroxymethylome.
Thomson JP, Lempiäinen H, Hackett JA, Nestor CE, Müller A, Bolognani F, Oakeley EJ, Schübeler D, Terranova R, Reinhardt D, Moggs JG, Meehan RR. Thomson JP, et al. Among authors: meehan rr. Genome Biol. 2012 Oct 3;13(10):R93. doi: 10.1186/gb-2012-13-10-r93. Genome Biol. 2012. PMID: 23034186 Free PMC article.
Redistribution of H3K27me3 upon DNA hypomethylation results in de-repression of Polycomb target genes.
Reddington JP, Perricone SM, Nestor CE, Reichmann J, Youngson NA, Suzuki M, Reinhardt D, Dunican DS, Prendergast JG, Mjoseng H, Ramsahoye BH, Whitelaw E, Greally JM, Adams IR, Bickmore WA, Meehan RR. Reddington JP, et al. Among authors: meehan rr. Genome Biol. 2013 Mar 25;14(3):R25. doi: 10.1186/gb-2013-14-3-r25. Genome Biol. 2013. PMID: 23531360 Free PMC article.
Epigenetic profiles as defined signatures of xenobiotic exposure.
Thomson JP, Moggs JG, Wolf CR, Meehan RR. Thomson JP, et al. Among authors: meehan rr. Mutat Res Genet Toxicol Environ Mutagen. 2014 Apr;764-765:3-9. doi: 10.1016/j.mrgentox.2013.08.007. Epub 2013 Aug 31. Mutat Res Genet Toxicol Environ Mutagen. 2014. PMID: 24001620 Review.
Hydroxymethylated DNA immunoprecipitation (hmeDIP).
Nestor CE, Meehan RR. Nestor CE, et al. Among authors: meehan rr. Methods Mol Biol. 2014;1094:259-67. doi: 10.1007/978-1-62703-706-8_20. Methods Mol Biol. 2014. PMID: 24162994
124 results