Guo L - Search Results

1

Allosteric modulation of sigma-1 receptors elicits anti-seizure activities.

Guo L, Chen Y, Zhao R, Wang G, Friedman E, Zhang A, Zhen X. Guo L, et al. Br J Pharmacol. 2015 Aug;172(16):4052-65. doi: 10.1111/bph.13195. Epub 2015 Jun 26. Br J Pharmacol. 2015. PMID: 25989224 Free PMC article.

2

Identification of N-propylnoraporphin-11-yl 5-(1,2-dithiolan-3-yl)pentanoate as a new anti-Parkinson's agent possessing a dopamine D2 and serotonin 5-HT1A dual-agonist profile.

Zhang H, Ye N, Zhou S, Guo L, Zheng L, Liu Z, Gao B, Zhen X, Zhang A. Zhang H, et al. Among authors: guo l. J Med Chem. 2011 Jul 14;54(13):4324-38. doi: 10.1021/jm200347t. Epub 2011 Jun 2. J Med Chem. 2011. PMID: 21591752

3

Synthesis and antidepressant activity of arylalkanol-piperidine derivatives as triple reuptake inhibitors.

Zheng YY, Guo L, Zhen XC, Li JQ. Zheng YY, et al. Among authors: guo l. Eur J Med Chem. 2012 Aug;54:123-36. doi: 10.1016/j.ejmech.2012.04.030. Epub 2012 Apr 30. Eur J Med Chem. 2012. PMID: 22608762

4

SKF83959 is a potent allosteric modulator of sigma-1 receptor.

Guo L, Zhao J, Jin G, Zhao B, Wang G, Zhang A, Zhen X. Guo L, et al. Mol Pharmacol. 2013 Mar;83(3):577-86. doi: 10.1124/mol.112.083840. Epub 2013 Jan 7. Mol Pharmacol. 2013. PMID: 23295385

5

Asymmetric total synthesis and identification of tetrahydroprotoberberine derivatives as new antipsychotic agents possessing a dopamine D(1), D(2) and serotonin 5-HT(1A) multi-action profile.

Sun H, Zhu L, Yang H, Qian W, Guo L, Zhou S, Gao B, Li Z, Zhou Y, Jiang H, Chen K, Zhen X, Liu H. Sun H, et al. Among authors: guo l. Bioorg Med Chem. 2013 Feb 15;21(4):856-68. doi: 10.1016/j.bmc.2012.12.016. Epub 2012 Dec 21. Bioorg Med Chem. 2013. PMID: 23332346

6

SKF83959 is a novel triple reuptake inhibitor that elicits anti-depressant activity.

Fang X, Guo L, Jia J, Jin GZ, Zhao B, Zheng YY, Li JQ, Zhang A, Zhen XC. Fang X, et al. Among authors: guo l. Acta Pharmacol Sin. 2013 Sep;34(9):1149-55. doi: 10.1038/aps.2013.66. Epub 2013 Jul 29. Acta Pharmacol Sin. 2013. PMID: 23892272 Free PMC article.

7

(6aR)-11-amino-N-propyl-noraporphine, a new dopamine D2 and serotonin 5-HT1A dual agonist, elicits potent antiparkinsonian action and attenuates levodopa-induced dyskinesia in a 6-OHDA-lesioned rat model of Parkinson's disease.

Zhao R, Lu W, Fang X, Guo L, Yang Z, Ye N, Zhao J, Liu Z, Jia J, Zheng L, Zhao B, Zhang A, Zhen X. Zhao R, et al. Among authors: guo l. Pharmacol Biochem Behav. 2014 Sep;124:204-10. doi: 10.1016/j.pbb.2014.06.011. Epub 2014 Jun 21. Pharmacol Biochem Behav. 2014. PMID: 24955866

8

Structural manipulation on the catecholic fragment of dopamine D(1) receptor agonist 1-phenyl-N-methyl-benzazepines.

Zhang J, Huang J, Song Z, Guo L, Cai W, Wang Y, Zhen X, Zhang A. Zhang J, et al. Among authors: guo l. Eur J Med Chem. 2014 Oct 6;85:16-26. doi: 10.1016/j.ejmech.2014.07.059. Epub 2014 Jul 24. Eur J Med Chem. 2014. PMID: 25076379

9

Design, synthesis and evaluation of benzo[a]thieno[3,2-g]quinolizines as novel l-SPD derivatives possessing dopamine D1, D2 and serotonin 5-HT1A multiple action profiles.

Li Z, Huang J, Sun H, Zhou S, Guo L, Zhou Y, Zhen X, Liu H. Li Z, et al. Among authors: guo l. Bioorg Med Chem. 2014 Nov 1;22(21):5838-46. doi: 10.1016/j.bmc.2014.09.024. Epub 2014 Sep 19. Bioorg Med Chem. 2014. PMID: 25308766

10

Sigma-2 receptor ligands: neurobiological effects.

Guo L, Zhen X. Guo L, et al. Curr Med Chem. 2015;22(8):989-1003. doi: 10.2174/0929867322666150114163607. Curr Med Chem. 2015. PMID: 25620095 Review.

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