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Page 1
Ghrelin and the endocrine pancreas.
Broglio F, Gottero C, Benso A, Prodam F, Volante M, Destefanis S, Gauna C, Muccioli G, Papotti M, van der Lely AJ, Ghigo E. Broglio F, et al. Among authors: van der lely aj. Endocrine. 2003 Oct;22(1):19-24. doi: 10.1385/ENDO:22:1:19. Endocrine. 2003. PMID: 14610295 Review.
Administration of acylated ghrelin reduces insulin sensitivity, whereas the combination of acylated plus unacylated ghrelin strongly improves insulin sensitivity.
Gauna C, Meyler FM, Janssen JA, Delhanty PJ, Abribat T, van Koetsveld P, Hofland LJ, Broglio F, Ghigo E, van der Lely AJ. Gauna C, et al. Among authors: van koetsveld p, van der lely aj. J Clin Endocrinol Metab. 2004 Oct;89(10):5035-42. doi: 10.1210/jc.2004-0363. J Clin Endocrinol Metab. 2004. PMID: 15472202 Clinical Trial.
Ghrelin and unacylated ghrelin stimulate human osteoblast growth via mitogen-activated protein kinase (MAPK)/phosphoinositide 3-kinase (PI3K) pathways in the absence of GHS-R1a.
Delhanty PJ, van der Eerden BC, van der Velde M, Gauna C, Pols HA, Jahr H, Chiba H, van der Lely AJ, van Leeuwen JP. Delhanty PJ, et al. Among authors: van leeuwen jp, van der lely aj, van der eerden bc, van der velde m. J Endocrinol. 2006 Jan;188(1):37-47. doi: 10.1677/joe.1.06404. J Endocrinol. 2006. PMID: 16394173
Unacylated ghrelin is active on the INS-1E rat insulinoma cell line independently of the growth hormone secretagogue receptor type 1a and the corticotropin releasing factor 2 receptor.
Gauna C, Delhanty PJ, van Aken MO, Janssen JA, Themmen AP, Hofland LJ, Culler M, Broglio F, Ghigo E, van der Lely AJ. Gauna C, et al. Among authors: van aken mo, van der lely aj. Mol Cell Endocrinol. 2006 Jun 7;251(1-2):103-11. doi: 10.1016/j.mce.2006.03.040. Epub 2006 Apr 27. Mol Cell Endocrinol. 2006. PMID: 16647196
Ghrelin and its unacylated isoform stimulate the growth of adrenocortical tumor cells via an anti-apoptotic pathway.
Delhanty PJ, van Koetsveld PM, Gauna C, van de Zande B, Vitale G, Hofland LJ, van der Lely AJ. Delhanty PJ, et al. Among authors: van koetsveld pm, van de zande b, van der lely aj. Am J Physiol Endocrinol Metab. 2007 Jul;293(1):E302-9. doi: 10.1152/ajpendo.00377.2006. Epub 2007 Apr 3. Am J Physiol Endocrinol Metab. 2007. PMID: 17405826 Free article.
Unacylated ghrelin acts as a potent insulin secretagogue in glucose-stimulated conditions.
Gauna C, Kiewiet RM, Janssen JA, van de Zande B, Delhanty PJ, Ghigo E, Hofland LJ, Themmen AP, van der Lely AJ. Gauna C, et al. Among authors: van de zande b, van der lely aj. Am J Physiol Endocrinol Metab. 2007 Sep;293(3):E697-704. doi: 10.1152/ajpendo.00219.2007. Epub 2007 Jun 19. Am J Physiol Endocrinol Metab. 2007. PMID: 17578884 Free article.
325 results