Gavin P - Search Results

1

Topical application of a novel oxycodone gel formulation (tocopheryl phosphate mixture) in a rat model of peripheral inflammatory pain produces localized pain relief without significant systemic exposure.

Smith MT, Wyse BD, Edwards SR, El-Tamimy M, Gaetano G, Gavin P. Smith MT, et al. Among authors: gavin p. J Pharm Sci. 2015 Jul;104(7):2388-96. doi: 10.1002/jps.24502. Epub 2015 May 20. J Pharm Sci. 2015. PMID: 25995048

2

Tocopheryl phosphate mixture (TPM) as a novel lipid-based transdermal drug delivery carrier: formulation and evaluation.

Gavin PD, El-Tamimy M, Keah HH, Boyd BJ. Gavin PD, et al. Drug Deliv Transl Res. 2017 Feb;7(1):53-65. doi: 10.1007/s13346-016-0331-x. Drug Deliv Transl Res. 2017. PMID: 27672079

3

Transdermal oxycodone patch for the treatment of postherpetic neuralgia: a randomized, double-blind, controlled trial.

Gavin PD, Tremper L, Smith A, Williams G, Brooker C. Gavin PD, et al. Pain Manag. 2017 Jul;7(4):255-267. doi: 10.2217/pmt-2016-0067. Epub 2017 Apr 18. Pain Manag. 2017. PMID: 28415907 Clinical Trial.

4

Pharmacokinetics, safety and tolerability of a novel tocopheryl phosphate mixture/oxycodone transdermal patch system: a Phase I study.

Gavin PD, Simon LS, Schlagheck T, Smith AJ, Shakib S. Gavin PD, et al. Pain Manag. 2017 Jul;7(4):243-253. doi: 10.2217/pmt-2016-0068. Epub 2017 Apr 19. Pain Manag. 2017. PMID: 28421874 Clinical Trial.

5

A Phase I study of the pharmacokinetics, safety and tolerability of a novel tocopheryl phosphate mixture/oxymorphone transdermal patch system.

Gavin PD, Simon LS, Schlagheck T, Smith AJ, Krishnarajah J. Gavin PD, et al. Pain Manag. 2017 Nov;7(6):499-512. doi: 10.2217/pmt-2017-0032. Epub 2017 Aug 17. Pain Manag. 2017. PMID: 28814158 Clinical Trial.

6

Changes in Bioavailability of Omega-3 (DHA) through Alpha-Tocopheryl Phosphate Mixture (TPM) after Oral Administration in Rats.

Libinaki R, Gavin PD. Libinaki R, et al. Nutrients. 2017 Sep 20;9(9):1042. doi: 10.3390/nu9091042. Nutrients. 2017. PMID: 28930161 Free PMC article.

7

An open-label feasibility trial of transdermal cannabidiol for hand osteoarthritis.

Bawa Z, Lewis D, Gavin PD, Libinaki R, Joubran L, El-Tamimy M, Taylor G, Meltzer R, Bedoya-Pérez M, Kevin RC, McGregor IS. Bawa Z, et al. Among authors: gavin pd. Sci Rep. 2024 May 23;14(1):11792. doi: 10.1038/s41598-024-62428-x. Sci Rep. 2024. PMID: 38783008 Free PMC article. Clinical Trial.

8

Alpha-tocopheryl phosphate: a novel, natural form of vitamin E.

Gianello R, Libinaki R, Azzi A, Gavin PD, Negis Y, Zingg JM, Holt P, Keah HH, Griffey A, Smallridge A, West SM, Ogru E. Gianello R, et al. Among authors: gavin pd. Free Radic Biol Med. 2005 Oct 1;39(7):970-6. doi: 10.1016/j.freeradbiomed.2005.05.016. Free Radic Biol Med. 2005. PMID: 16140216

9

A new lipid excipient, phosphorylated tocopherol mixture, TPM enhances the solubilisation and oral bioavailability of poorly water soluble CoQ₁₀ in a lipid formulation.

Pham AC, Gavin P, Libinaki R, Ramirez G, Boyd BJ. Pham AC, et al. Among authors: gavin p. J Control Release. 2017 Dec 28;268:400-406. doi: 10.1016/j.jconrel.2017.10.039. Epub 2017 Oct 31. J Control Release. 2017. PMID: 29097302

10

Differential Effects of TPM, A Phosphorylated Tocopherol Mixture, and Other Tocopherol Derivatives as Excipients for Enhancing the Solubilization of Co-Enzyme Q10 as a Lipophilic Drug During Digestion of Lipid- Based Formulations.

Pham A, Gavin PD, Libinaki R, Ramirez G, Khan JT, Boyd BJ. Pham A, et al. Curr Drug Deliv. 2019;16(7):628-636. doi: 10.2174/1567201816666190806114022. Curr Drug Deliv. 2019. PMID: 31385769

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