Luo HR - Search Results

1

Fyn-phosphorylated PIKE-A binds and inhibits AMPK signaling, blocking its tumor suppressive activity.

Zhang S, Qi Q, Chan CB, Zhou W, Chen J, Luo HR, Appin C, Brat DJ, Ye K. Zhang S, et al. Among authors: luo hr. Cell Death Differ. 2016 Jan;23(1):52-63. doi: 10.1038/cdd.2015.66. Epub 2015 May 22. Cell Death Differ. 2016. PMID: 26001218 Free PMC article.

2

Pike. A nuclear gtpase that enhances PI3kinase activity and is regulated by protein 4.1N.

Ye K, Hurt KJ, Wu FY, Fang M, Luo HR, Hong JJ, Blackshaw S, Ferris CD, Snyder SH. Ye K, et al. Among authors: luo hr. Cell. 2000 Dec 8;103(6):919-30. doi: 10.1016/s0092-8674(00)00195-1. Cell. 2000. PMID: 11136977 Free article.

3

Phospholipase C gamma 1 is a physiological guanine nucleotide exchange factor for the nuclear GTPase PIKE.

Ye K, Aghdasi B, Luo HR, Moriarity JL, Wu FY, Hong JJ, Hurt KJ, Bae SS, Suh PG, Snyder SH. Ye K, et al. Among authors: luo hr. Nature. 2002 Jan 31;415(6871):541-4. doi: 10.1038/415541a. Nature. 2002. PMID: 11823862

4

Inositol pyrophosphates mediate chemotaxis in Dictyostelium via pleckstrin homology domain-PtdIns(3,4,5)P3 interactions.

Luo HR, Huang YE, Chen JC, Saiardi A, Iijima M, Ye K, Huang Y, Nagata E, Devreotes P, Snyder SH. Luo HR, et al. Cell. 2003 Sep 5;114(5):559-72. doi: 10.1016/s0092-8674(03)00640-8. Cell. 2003. PMID: 13678580 Free article.

5

Neuroprotective actions of PIKE-L by inhibition of SET proteolytic degradation by asparagine endopeptidase.

Liu Z, Jang SW, Liu X, Cheng D, Peng J, Yepes M, Li XJ, Matthews S, Watts C, Asano M, Hara-Nishimura I, Luo HR, Ye K. Liu Z, et al. Among authors: luo hr. Mol Cell. 2008 Mar 28;29(6):665-78. doi: 10.1016/j.molcel.2008.02.017. Mol Cell. 2008. PMID: 18374643 Free PMC article.

6

Targeted deletion of tumor suppressor PTEN augments neutrophil function and enhances host defense in neutropenia-associated pneumonia.

Li Y, Jia Y, Pichavant M, Loison F, Sarraj B, Kasorn A, You J, Robson BE, Umetsu DT, Mizgerd JP, Ye K, Luo HR. Li Y, et al. Among authors: luo hr. Blood. 2009 May 14;113(20):4930-41. doi: 10.1182/blood-2008-06-161414. Epub 2009 Mar 13. Blood. 2009. PMID: 19286998 Free PMC article.

7

Deficiency of phosphoinositide 3-kinase enhancer protects mice from diet-induced obesity and insulin resistance.

Chan CB, Liu X, Jung DY, Jun JY, Luo HR, Kim JK, Ye K. Chan CB, et al. Among authors: luo hr. Diabetes. 2010 Apr;59(4):883-93. doi: 10.2337/db09-1404. Epub 2010 Jan 12. Diabetes. 2010. PMID: 20068140 Free PMC article.

8

A synthetic 7,8-dihydroxyflavone derivative promotes neurogenesis and exhibits potent antidepressant effect.

Liu X, Chan CB, Jang SW, Pradoldej S, Huang J, He K, Phun LH, France S, Xiao G, Jia Y, Luo HR, Ye K. Liu X, et al. Among authors: luo hr. J Med Chem. 2010 Dec 9;53(23):8274-86. doi: 10.1021/jm101206p. Epub 2010 Nov 12. J Med Chem. 2010. PMID: 21073191 Free PMC article.

9

Deactivation of Akt by a small molecule inhibitor targeting pleckstrin homology domain and facilitating Akt ubiquitination.

Jo H, Lo PK, Li Y, Loison F, Green S, Wang J, Silberstein LE, Ye K, Chen H, Luo HR. Jo H, et al. Among authors: luo hr. Proc Natl Acad Sci U S A. 2011 Apr 19;108(16):6486-91. doi: 10.1073/pnas.1019062108. Epub 2011 Apr 4. Proc Natl Acad Sci U S A. 2011. PMID: 21464312 Free PMC article.

10

Phosphoinositide 3-kinase enhancer regulates neuronal dendritogenesis and survival in neocortex.

Chan CB, Liu X, Pradoldej S, Hao C, An J, Yepes M, Luo HR, Ye K. Chan CB, et al. Among authors: luo hr. J Neurosci. 2011 Jun 1;31(22):8083-92. doi: 10.1523/JNEUROSCI.1129-11.2011. J Neurosci. 2011. PMID: 21632930 Free PMC article.

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