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Page 1
Translational regulation shapes the molecular landscape of complex disease phenotypes.
Schafer S, Adami E, Heinig M, Rodrigues KEC, Kreuchwig F, Silhavy J, van Heesch S, Simaite D, Rajewsky N, Cuppen E, Pravenec M, Vingron M, Cook SA, Hubner N. Schafer S, et al. Among authors: van heesch s. Nat Commun. 2015 May 26;6:7200. doi: 10.1038/ncomms8200. Nat Commun. 2015. PMID: 26007203 Free PMC article.
Quantitative and qualitative proteome characteristics extracted from in-depth integrated genomics and proteomics analysis.
Low TY, van Heesch S, van den Toorn H, Giansanti P, Cristobal A, Toonen P, Schafer S, Hübner N, van Breukelen B, Mohammed S, Cuppen E, Heck AJ, Guryev V. Low TY, et al. Among authors: van den toorn h, van heesch s, van breukelen b. Cell Rep. 2013 Dec 12;5(5):1469-78. doi: 10.1016/j.celrep.2013.10.041. Epub 2013 Nov 27. Cell Rep. 2013. PMID: 24290761 Free article.
Large-scale identification of coregulated enhancer networks in the adult human brain.
Vermunt MW, Reinink P, Korving J, de Bruijn E, Creyghton PM, Basak O, Geeven G, Toonen PW, Lansu N, Meunier C, van Heesch S; Netherlands Brain Bank; Clevers H, de Laat W, Cuppen E, Creyghton MP. Vermunt MW, et al. Among authors: van heesch s. Cell Rep. 2014 Oct 23;9(2):767-79. doi: 10.1016/j.celrep.2014.09.023. Epub 2014 Oct 16. Cell Rep. 2014. PMID: 25373911 Free article.
Lack of major genome instability in tumors of p53 null rats.
Hermsen R, Toonen P, Kuijk E, Youssef SA, Kuiper R, van Heesch S, de Bruin A, Cuppen E, Simonis M. Hermsen R, et al. Among authors: van heesch s. PLoS One. 2015 Mar 26;10(3):e0122066. doi: 10.1371/journal.pone.0122066. eCollection 2015. PLoS One. 2015. PMID: 25811670 Free PMC article.
Titin-truncating variants affect heart function in disease cohorts and the general population.
Schafer S, de Marvao A, Adami E, Fiedler LR, Ng B, Khin E, Rackham OJ, van Heesch S, Pua CJ, Kui M, Walsh R, Tayal U, Prasad SK, Dawes TJ, Ko NS, Sim D, Chan LL, Chin CW, Mazzarotto F, Barton PJ, Kreuchwig F, de Kleijn DP, Totman T, Biffi C, Tee N, Rueckert D, Schneider V, Faber A, Regitz-Zagrosek V, Seidman JG, Seidman CE, Linke WA, Kovalik JP, O'Regan D, Ware JS, Hubner N, Cook SA. Schafer S, et al. Among authors: van heesch s. Nat Genet. 2017 Jan;49(1):46-53. doi: 10.1038/ng.3719. Epub 2016 Nov 21. Nat Genet. 2017. PMID: 27869827 Free PMC article.
Epigenetics and Control of RNAs.
Maatz H, van Heesch S, Kreuchwig F, Faber A, Adami E, Hubner N, Heinig M. Maatz H, et al. Among authors: van heesch s. Methods Mol Biol. 2017;1488:217-237. doi: 10.1007/978-1-4939-6427-7_9. Methods Mol Biol. 2017. PMID: 27933526
45 results