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Page 1
A 4-week high-AGE diet does not impair glucose metabolism and vascular function in obese individuals.
Linkens AM, Houben AJ, Niessen PM, Wijckmans NE, de Goei EE, Van den Eynde MD, Scheijen JL, van den Waarenburg MP, Mari A, Berendschot TT, Streese L, Hanssen H, van Dongen MC, van Gool CC, Stehouwer CD, Eussen SJ, Schalkwijk CG. Linkens AM, et al. JCI Insight. 2022 Mar 22;7(6):e156950. doi: 10.1172/jci.insight.156950. JCI Insight. 2022. PMID: 35133989 Free PMC article. Clinical Trial.
A 4-Week Diet Low or High in Advanced Glycation Endproducts Has Limited Impact on Gut Microbial Composition in Abdominally Obese Individuals: The deAGEing Trial.
Linkens AMA, van Best N, Niessen PM, Wijckmans NEG, de Goei EEC, Scheijen JLJM, van Dongen MCJM, van Gool CCJAW, de Vos WM, Houben AJHM, Stehouwer CDA, Eussen SJMP, Penders J, Schalkwijk CG. Linkens AMA, et al. Int J Mol Sci. 2022 May 10;23(10):5328. doi: 10.3390/ijms23105328. Int J Mol Sci. 2022. PMID: 35628138 Free PMC article. Clinical Trial.
Dietary advanced glycation endproducts (AGEs) increase their concentration in plasma and tissues, result in inflammation and modulate gut microbial composition in mice; evidence for reversibility.
van Dongen KCW, Linkens AMA, Wetzels SMW, Wouters K, Vanmierlo T, van de Waarenburg MPH, Scheijen JLJM, de Vos WM, Belzer C, Schalkwijk CG. van Dongen KCW, et al. Among authors: linkens ama. Food Res Int. 2021 Sep;147:110547. doi: 10.1016/j.foodres.2021.110547. Epub 2021 Jun 18. Food Res Int. 2021. PMID: 34399524
Pyridoxamine reduces methylglyoxal and markers of glycation and endothelial dysfunction, but does not improve insulin sensitivity or vascular function in abdominally obese individuals: A randomized double-blind placebo-controlled trial.
Van den Eynde MDG, Houben AJHM, Scheijen JLJM, Linkens AMA, Niessen PM, Simons N, Hanssen NMJ, Kusters YHAM, Eussen SJMP, Miyata T, Stehouwer CDA, Schalkwijk CG. Van den Eynde MDG, et al. Among authors: linkens ama. Diabetes Obes Metab. 2023 May;25(5):1280-1291. doi: 10.1111/dom.14977. Epub 2023 Feb 14. Diabetes Obes Metab. 2023. PMID: 36655410 Clinical Trial.