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Treatment of inflammatory arthritis via targeting of tristetraprolin, a master regulator of pro-inflammatory gene expression.
Ross EA, Naylor AJ, O'Neil JD, Crowley T, Ridley ML, Crowe J, Smallie T, Tang TJ, Turner JD, Norling LV, Dominguez S, Perlman H, Verrills NM, Kollias G, Vitek MP, Filer A, Buckley CD, Dean JL, Clark AR. Ross EA, et al. Among authors: tang tj. Ann Rheum Dis. 2017 Mar;76(3):612-619. doi: 10.1136/annrheumdis-2016-209424. Epub 2016 Sep 5. Ann Rheum Dis. 2017. PMID: 27597652 Free PMC article.
Gain-of-Function Mutation of Tristetraprolin Impairs Negative Feedback Control of Macrophages In Vitro yet Has Overwhelmingly Anti-Inflammatory Consequences In Vivo.
O'Neil JD, Ross EA, Ridley ML, Ding Q, Tang T, Rosner DR, Crowley T, Malhi D, Dean JL, Smallie T, Buckley CD, Clark AR. O'Neil JD, et al. Among authors: tang t. Mol Cell Biol. 2017 May 16;37(11):e00536-16. doi: 10.1128/MCB.00536-16. Print 2017 Jun 1. Mol Cell Biol. 2017. PMID: 28265004 Free PMC article.
Dexamethasone impairs the expression of antimicrobial mediators in lipopolysaccharide-activated primary macrophages by inhibiting both expression and function of interferon β.
O'Neil JD, Bolimowska OO, Clayton SA, Tang T, Daley KK, Lara-Reyna S, Warner J, Martin CS, Mahida RY, Hardy RS, Arthur JSC, Clark AR. O'Neil JD, et al. Among authors: tang t. Front Immunol. 2023 Oct 24;14:1190261. doi: 10.3389/fimmu.2023.1190261. eCollection 2023. Front Immunol. 2023. PMID: 37942320 Free PMC article.
Ex vivo modelling of PD-1/PD-L1 immune checkpoint blockade under acute, chronic, and exhaustion-like conditions of T-cell stimulation.
Roberts A, Bentley L, Tang T, Stewart F, Pallini C, Juvvanapudi J, Wallace GR, Cooper AJ, Scott A, Thickett D, Lugg ST, Bancroft H, Hemming B, Ferris C, Langman G, Robinson A, Chapman J, Naidu B, Pinkney T, Taylor GS, Brock K, Stamataki Z, Brady CA, Curnow SJ, Gordon J, Qureshi O, Barnes NM. Roberts A, et al. Among authors: tang t. Sci Rep. 2021 Feb 17;11(1):4030. doi: 10.1038/s41598-021-83612-3. Sci Rep. 2021. PMID: 33597595 Free PMC article.
5,351 results