Challis GL - Search Results

1

Stereochemistry and Mechanism of Undecylprodigiosin Oxidative Carbocyclization to Streptorubin B by the Rieske Oxygenase RedG.

Withall DM, Haynes SW, Challis GL. Withall DM, et al. Among authors: challis gl. J Am Chem Soc. 2015 Jun 24;137(24):7889-97. doi: 10.1021/jacs.5b03994. Epub 2015 Jun 12. J Am Chem Soc. 2015. PMID: 26023709

2

Identification of a cluster of genes that directs desferrioxamine biosynthesis in Streptomyces coelicolor M145.

Barona-Gómez F, Wong U, Giannakopulos AE, Derrick PJ, Challis GL. Barona-Gómez F, et al. Among authors: challis gl. J Am Chem Soc. 2004 Dec 22;126(50):16282-3. doi: 10.1021/ja045774k. J Am Chem Soc. 2004. PMID: 15600304

3

Elucidation of the Streptomyces coelicolor pathway to 4-methoxy-2,2'-bipyrrole-5-carboxaldehyde, an intermediate in prodiginine biosynthesis.

Stanley AE, Walton LJ, Kourdi Zerikly M, Corre C, Challis GL. Stanley AE, et al. Among authors: challis gl. Chem Commun (Camb). 2006 Oct 14;(38):3981-3. doi: 10.1039/b609556a. Epub 2006 Sep 11. Chem Commun (Camb). 2006. PMID: 17003872

4

Type III polyketide synthase beta-ketoacyl-ACP starter unit and ethylmalonyl-CoA extender unit selectivity discovered by Streptomyces coelicolor genome mining.

Song L, Barona-Gomez F, Corre C, Xiang L, Udwary DW, Austin MB, Noel JP, Moore BS, Challis GL. Song L, et al. Among authors: challis gl. J Am Chem Soc. 2006 Nov 22;128(46):14754-5. doi: 10.1021/ja065247w. J Am Chem Soc. 2006. PMID: 17105255 Free PMC article.

5

Non-linear enzymatic logic in natural product modular mega-synthases and -synthetases.

Haynes SW, Challis GL. Haynes SW, et al. Among authors: challis gl. Curr Opin Drug Discov Devel. 2007 Mar;10(2):203-18. Curr Opin Drug Discov Devel. 2007. PMID: 17436556 Review.

6

Enzymatic logic of anthrax stealth siderophore biosynthesis: AsbA catalyzes ATP-dependent condensation of citric acid and spermidine.

Oves-Costales D, Kadi N, Fogg MJ, Song L, Wilson KS, Challis GL. Oves-Costales D, et al. Among authors: challis gl. J Am Chem Soc. 2007 Jul 11;129(27):8416-7. doi: 10.1021/ja072391o. Epub 2007 Jun 19. J Am Chem Soc. 2007. PMID: 17579415 No abstract available.

7

A new family of ATP-dependent oligomerization-macrocyclization biocatalysts.

Kadi N, Oves-Costales D, Barona-Gomez F, Challis GL. Kadi N, et al. Among authors: challis gl. Nat Chem Biol. 2007 Oct;3(10):652-6. doi: 10.1038/nchembio.2007.23. Epub 2007 Aug 19. Nat Chem Biol. 2007. PMID: 17704771

8

Elucidation of the Streptomyces coelicolor pathway to 2-undecylpyrrole, a key intermediate in undecylprodiginine and streptorubin B biosynthesis.

Mo S, Sydor PK, Corre C, Alhamadsheh MM, Stanley AE, Haynes SW, Song L, Reynolds KA, Challis GL. Mo S, et al. Among authors: challis gl. Chem Biol. 2008 Feb;15(2):137-48. doi: 10.1016/j.chembiol.2007.11.015. Chem Biol. 2008. PMID: 18291318

9

Role and substrate specificity of the Streptomyces coelicolor RedH enzyme in undecylprodiginine biosynthesis.

Haynes SW, Sydor PK, Stanley AE, Song L, Challis GL. Haynes SW, et al. Among authors: challis gl. Chem Commun (Camb). 2008 Apr 28;(16):1865-7. doi: 10.1039/b801677a. Epub 2008 Mar 14. Chem Commun (Camb). 2008. PMID: 18401500

10

Identification of a gene cluster that directs putrebactin biosynthesis in Shewanella species: PubC catalyzes cyclodimerization of N-hydroxy-N-succinylputrescine.

Kadi N, Arbache S, Song L, Oves-Costales D, Challis GL. Kadi N, et al. Among authors: challis gl. J Am Chem Soc. 2008 Aug 13;130(32):10458-9. doi: 10.1021/ja8027263. Epub 2008 Jul 17. J Am Chem Soc. 2008. PMID: 18630910

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