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Responding to the challenge of untreatable gonorrhea: ETX0914, a first-in-class agent with a distinct mechanism-of-action against bacterial Type II topoisomerases.
Basarab GS, Kern GH, McNulty J, Mueller JP, Lawrence K, Vishwanathan K, Alm RA, Barvian K, Doig P, Galullo V, Gardner H, Gowravaram M, Huband M, Kimzey A, Morningstar M, Kutschke A, Lahiri SD, Perros M, Singh R, Schuck VJ, Tommasi R, Walkup G, Newman JV. Basarab GS, et al. Among authors: singh r. Sci Rep. 2015 Jul 14;5:11827. doi: 10.1038/srep11827. Sci Rep. 2015. PMID: 26168713 Free PMC article. Clinical Trial.
Mathematical modeling to characterize the inoculum effect.
Bhagunde P, Chang KT, Singh R, Singh V, Garey KW, Nikolaou M, Tam VH. Bhagunde P, et al. Among authors: singh v, singh r. Antimicrob Agents Chemother. 2010 Nov;54(11):4739-43. doi: 10.1128/AAC.01831-09. Epub 2010 Aug 30. Antimicrob Agents Chemother. 2010. PMID: 20805390 Free PMC article.
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