Sheng C - Search Results

1

Discovery of benzylidene derivatives as potent Syk inhibitors: synthesis, SAR analysis, and biological evaluation.

Zhang L, Liu W, Mao F, Zhu J, Dong G, Jiang H, Sheng C, Miao L, Huang L, Li J. Zhang L, et al. Among authors: sheng c. Arch Pharm (Weinheim). 2015 Jul;348(7):463-74. doi: 10.1002/ardp.201500096. Epub 2015 Jun 1. Arch Pharm (Weinheim). 2015. PMID: 26032727

2

Homology modeling and molecular dynamics simulation of N-myristoyltransferase from protozoan parasites: active site characterization and insights into rational inhibitor design.

Sheng C, Ji H, Miao Z, Che X, Yao J, Wang W, Dong G, Guo W, Lü J, Zhang W. Sheng C, et al. J Comput Aided Mol Des. 2009 Jun;23(6):375-89. doi: 10.1007/s10822-009-9267-2. Epub 2009 Apr 16. J Comput Aided Mol Des. 2009. PMID: 19370313

3

Three-dimensional model of lanosterol 14 alpha-demethylase from Cryptococcus neoformans: active-site characterization and insights into azole binding.

Sheng C, Miao Z, Ji H, Yao J, Wang W, Che X, Dong G, Lü J, Guo W, Zhang W. Sheng C, et al. Antimicrob Agents Chemother. 2009 Aug;53(8):3487-95. doi: 10.1128/AAC.01630-08. Epub 2009 May 26. Antimicrob Agents Chemother. 2009. PMID: 19470512 Free PMC article.

4

New azoles with potent antifungal activity: design, synthesis and molecular docking.

Che X, Sheng C, Wang W, Cao Y, Xu Y, Ji H, Dong G, Miao Z, Yao J, Zhang W. Che X, et al. Among authors: sheng c. Eur J Med Chem. 2009 Oct;44(10):4218-26. doi: 10.1016/j.ejmech.2009.05.018. Epub 2009 May 24. Eur J Med Chem. 2009. PMID: 19539408

5

Evolutionary trace analysis of CYP51 family: implication for site-directed mutagenesis and novel antifungal drug design.

Sheng C, Chen S, Ji H, Dong G, Che X, Wang W, Miao Z, Yao J, Lü J, Guo W, Zhang W. Sheng C, et al. J Mol Model. 2010 Feb;16(2):279-84. doi: 10.1007/s00894-009-0527-9. Epub 2009 Jul 11. J Mol Model. 2010. PMID: 19593597

6

Design, synthesis, and antifungal activity of novel conformationally restricted triazole derivatives.

Wang W, Sheng C, Che X, Ji H, Miao Z, Yao J, Zhang WN. Wang W, et al. Among authors: sheng c. Arch Pharm (Weinheim). 2009 Dec;342(12):732-9. doi: 10.1002/ardp.200900103. Arch Pharm (Weinheim). 2009. PMID: 19899102

7

Design, synthesis, and antihepatitis B virus activities of novel 2-pyridone derivatives.

Lv Z, Sheng C, Wang T, Zhang Y, Liu J, Feng J, Sun H, Zhong H, Niu C, Li K. Lv Z, et al. Among authors: sheng c. J Med Chem. 2010 Jan 28;53(2):660-8. doi: 10.1021/jm901237x. J Med Chem. 2010. PMID: 20000776

8

Improved model of lanosterol 14alpha-demethylase by ligand-supported homology modeling: validation by virtual screening and azole optimization.

Sheng C, Wang W, Che X, Dong G, Wang S, Ji H, Miao Z, Yao J, Zhang W. Sheng C, et al. ChemMedChem. 2010 Mar 1;5(3):390-7. doi: 10.1002/cmdc.200900468. ChemMedChem. 2010. PMID: 20157915

9

Synthesis and evaluation of 9-benzylideneamino derivatives of homocamptothecin as potent inhibitors of DNA topoisomerase I.

Guo W, Miao Z, Sheng C, Yao J, Feng H, Zhang W, Zhu L, Liu W, Cheng P, Zhang J, Che X, Wang W, Luo C, Xu Y. Guo W, et al. Among authors: sheng c. Eur J Med Chem. 2010 Jun;45(6):2223-8. doi: 10.1016/j.ejmech.2010.01.063. Epub 2010 Feb 1. Eur J Med Chem. 2010. PMID: 20202723

10

Structure-based rational design, synthesis and antifungal activity of oxime-containing azole derivatives.

Xu Y, Sheng C, Wang W, Che X, Cao Y, Dong G, Wang S, Ji H, Miao Z, Yao J, Zhang W. Xu Y, et al. Among authors: sheng c. Bioorg Med Chem Lett. 2010 May 1;20(9):2942-5. doi: 10.1016/j.bmcl.2010.03.014. Epub 2010 Mar 7. Bioorg Med Chem Lett. 2010. PMID: 20362444

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