Varney MA - Search Results

1

NLX-112, a novel 5-HT1A receptor agonist for the treatment of L-DOPA-induced dyskinesia: Behavioral and neurochemical profile in rat.

Iderberg H, McCreary AC, Varney MA, Kleven MS, Koek W, Bardin L, Depoortère R, Cenci MA, Newman-Tancredi A. Iderberg H, et al. Among authors: varney ma. Exp Neurol. 2015 Sep;271:335-50. doi: 10.1016/j.expneurol.2015.05.021. Epub 2015 May 30. Exp Neurol. 2015. PMID: 26037043

2

Characterizing the differential roles of striatal 5-HT_1A auto- and hetero-receptors in the reduction of l-DOPA-induced dyskinesia.

Meadows SM, Chambers NE, Conti MM, Bossert SC, Tasber C, Sheena E, Varney M, Newman-Tancredi A, Bishop C. Meadows SM, et al. Exp Neurol. 2017 Jun;292:168-178. doi: 10.1016/j.expneurol.2017.03.013. Epub 2017 Mar 23. Exp Neurol. 2017. PMID: 28342749

3

Neurophysiological effects in cortico-basal ganglia-thalamic circuits of antidyskinetic treatment with 5-HT_1A receptor biased agonists.

Brys I, Halje P, Scheffer-Teixeira R, Varney M, Newman-Tancredi A, Petersson P. Brys I, et al. Exp Neurol. 2018 Apr;302:155-168. doi: 10.1016/j.expneurol.2018.01.010. Epub 2018 Jan 13. Exp Neurol. 2018. PMID: 29339052

4

The novel 5-HT1A receptor agonist, NLX-112 reduces l-DOPA-induced abnormal involuntary movements in rat: A chronic administration study with microdialysis measurements.

McCreary AC, Varney MA, Newman-Tancredi A. McCreary AC, et al. Among authors: varney ma. Neuropharmacology. 2016 Jun;105:651-660. doi: 10.1016/j.neuropharm.2016.01.013. Epub 2016 Jan 9. Neuropharmacology. 2016. PMID: 26777281

5

Effects of the Serotonin 5-HT_1A Receptor Biased Agonists, F13714 and F15599, on Striatal Neurotransmitter Levels Following L-DOPA Administration in Hemi-Parkinsonian Rats.

Newman-Tancredi A, Varney MA, McCreary AC. Newman-Tancredi A, et al. Among authors: varney ma. Neurochem Res. 2018 May;43(5):1035-1046. doi: 10.1007/s11064-018-2514-y. Epub 2018 Mar 23. Neurochem Res. 2018. PMID: 29572645

6

Serotonin 5-HT_1A Receptor Biased Agonists Display Differential Anxiolytic Activity in a Rat Social Interaction Model.

Depoortère R, Bardin L, Varney MA, Newman-Tancredi A. Depoortère R, et al. Among authors: varney ma. ACS Chem Neurosci. 2019 Jul 17;10(7):3101-3107. doi: 10.1021/acschemneuro.8b00661. Epub 2019 Apr 2. ACS Chem Neurosci. 2019. PMID: 30929419

7

Cortical 5-hydroxytryptamine 1A receptor biased agonist, NLX-101, displays rapid-acting antidepressant-like properties in the rat chronic mild stress model.

Depoortère R, Papp M, Gruca P, Lason-Tyburkiewicz M, Niemczyk M, Varney MA, Newman-Tancredi A. Depoortère R, et al. Among authors: varney ma. J Psychopharmacol. 2019 Nov;33(11):1456-1466. doi: 10.1177/0269881119860666. Epub 2019 Jul 10. J Psychopharmacol. 2019. PMID: 31290370

8

The selective 5-HT_1A receptor agonist, NLX-112, exerts anti-dyskinetic and anti-parkinsonian-like effects in MPTP-treated marmosets.

Fisher R, Hikima A, Morris R, Jackson MJ, Rose S, Varney MA, Depoortere R, Newman-Tancredi A. Fisher R, et al. Among authors: varney ma. Neuropharmacology. 2020 May 1;167:107997. doi: 10.1016/j.neuropharm.2020.107997. Epub 2020 Feb 10. Neuropharmacology. 2020. PMID: 32057799 Free PMC article.

9

The selective 5-HT 1A receptor agonist, NLX-112, overcomes tetrabenazine-induced catalepsy and depression-like behavior in the rat.

Jastrzębska-Więsek M, Wesołowska A, Kołaczkowski M, Varney MA, Newman-Tancredi A, Depoortere R. Jastrzębska-Więsek M, et al. Among authors: varney ma. Behav Pharmacol. 2022 Aug 1;33(5):333-341. doi: 10.1097/FBP.0000000000000681. Epub 2022 Jun 9. Behav Pharmacol. 2022. PMID: 35695543

10

Activity of serotonin 5-HT(1A) receptor 'biased agonists' in rat models of Parkinson's disease and L-DOPA-induced dyskinesia.

Iderberg H, McCreary AC, Varney MA, Cenci MA, Newman-Tancredi A. Iderberg H, et al. Among authors: varney ma. Neuropharmacology. 2015 Jun;93:52-67. doi: 10.1016/j.neuropharm.2015.01.012. Epub 2015 Jan 31. Neuropharmacology. 2015. PMID: 25645393

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