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New small molecules targeting apoptosis and cell viability in osteosarcoma.
Maugg D, Rothenaigner I, Schorpp K, Potukuchi HK, Korsching E, Baumhoer D, Hadian K, Smida J, Nathrath M. Maugg D, et al. Among authors: rothenaigner i. PLoS One. 2015 Jun 3;10(6):e0129058. doi: 10.1371/journal.pone.0129058. eCollection 2015. PLoS One. 2015. PMID: 26039064 Free PMC article.
Targeting TRAF6 E3 ligase activity with a small-molecule inhibitor combats autoimmunity.
Brenke JK, Popowicz GM, Schorpp K, Rothenaigner I, Roesner M, Meininger I, Kalinski C, Ringelstetter L, R'kyek O, Jürjens G, Vincendeau M, Plettenburg O, Sattler M, Krappmann D, Hadian K. Brenke JK, et al. Among authors: rothenaigner i. J Biol Chem. 2018 Aug 24;293(34):13191-13203. doi: 10.1074/jbc.RA118.002649. Epub 2018 Jun 27. J Biol Chem. 2018. PMID: 29950522 Free PMC article.
Image-based high-content screening in drug discovery.
Lin S, Schorpp K, Rothenaigner I, Hadian K. Lin S, et al. Among authors: rothenaigner i. Drug Discov Today. 2020 Aug;25(8):1348-1361. doi: 10.1016/j.drudis.2020.06.001. Epub 2020 Jun 16. Drug Discov Today. 2020. PMID: 32561299 Review.
Nuisance compounds in cellular assays.
Dahlin JL, Auld DS, Rothenaigner I, Haney S, Sexton JZ, Nissink JWM, Walsh J, Lee JA, Strelow JM, Willard FS, Ferrins L, Baell JB, Walters MA, Hua BK, Hadian K, Wagner BK. Dahlin JL, et al. Among authors: rothenaigner i. Cell Chem Biol. 2021 Mar 18;28(3):356-370. doi: 10.1016/j.chembiol.2021.01.021. Epub 2021 Feb 15. Cell Chem Biol. 2021. PMID: 33592188 Free PMC article. Review.
31 results