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Targeted therapy of AML new concepts.
Andreeff M, Milella M, Carter BZ, Tabe Y, Ricciardi MR, Sneed T, Ruvolo P, Contractor R, Tsao T, Schober W, Evans R, McQueen T, Zeng Z, Kornblau SM, McCubrey J, Estey E, Mills GB, Reed JC, Konopleva M. Andreeff M, et al. Ann Hematol. 2004;83 Suppl 1:S51-3. doi: 10.1007/s00277-004-0849-8. Ann Hematol. 2004. PMID: 15124670 No abstract available.
2-Cyano-3,12-dioxooleana-1,9-dien-28-imidazolide (CDDO-Im) directly targets mitochondrial glutathione to induce apoptosis in pancreatic cancer.
Samudio I, Konopleva M, Hail N Jr, Shi YX, McQueen T, Hsu T, Evans R, Honda T, Gribble GW, Sporn M, Gilbert HF, Safe S, Andreeff M. Samudio I, et al. Among authors: andreeff m. J Biol Chem. 2005 Oct 28;280(43):36273-82. doi: 10.1074/jbc.M507518200. Epub 2005 Aug 23. J Biol Chem. 2005. PMID: 16118208 Free article.
Mdm2 inhibitor Nutlin-3a induces p53-mediated apoptosis by transcription-dependent and transcription-independent mechanisms and may overcome Atm-mediated resistance to fludarabine in chronic lymphocytic leukemia.
Kojima K, Konopleva M, McQueen T, O'Brien S, Plunkett W, Andreeff M. Kojima K, et al. Among authors: andreeff m. Blood. 2006 Aug 1;108(3):993-1000. doi: 10.1182/blood-2005-12-5148. Epub 2006 Mar 16. Blood. 2006. PMID: 16543464 Free PMC article.
795 results