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A Glycyrrhizin Derivative with a More Potent Inhibitory Activity against High-Mobility Group Box 1 Efficiently Discovered by Chemical Synthesis Inspired by the Bioconversion Products of an Endophytic Fungus Isolated from Licorice.
Machida A, Banshoya K, Miyamaru A, Eto T, Maehara S, Hieda Y, Hata T, Ohnishi M. Machida A, et al. Among authors: ohnishi m. J Med Chem. 2024 Sep 26;67(18):16328-16337. doi: 10.1021/acs.jmedchem.4c01213. Epub 2024 Sep 4. J Med Chem. 2024. PMID: 39231005
In silico gepotidacin target mining among 33 213 global Neisseria gonorrhoeae genomes from 1928 to 2023 combined with gepotidacin MIC testing of 22 gonococcal isolates with different GyrA and ParC substitutions.
David A, Golparian D, Jacobsson S, Stratton C, Lan PT, Shimuta K, Sonnenberg P, Field N, Ohnishi M, Davies C, Unemo M. David A, et al. Among authors: ohnishi m. J Antimicrob Chemother. 2024 Sep 3;79(9):2221-2226. doi: 10.1093/jac/dkae217. J Antimicrob Chemother. 2024. PMID: 39004438 Free PMC article.
1,214 results