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PHYSIOLOGY. Regulation of breathing by CO₂ requires the proton-activated receptor GPR4 in retrotrapezoid nucleus neurons.
Kumar NN, Velic A, Soliz J, Shi Y, Li K, Wang S, Weaver JL, Sen J, Abbott SB, Lazarenko RM, Ludwig MG, Perez-Reyes E, Mohebbi N, Bettoni C, Gassmann M, Suply T, Seuwen K, Guyenet PG, Wagner CA, Bayliss DA. Kumar NN, et al. Among authors: seuwen k. Science. 2015 Jun 12;348(6240):1255-60. doi: 10.1126/science.aaa0922. Epub 2015 Jun 11. Science. 2015. PMID: 26068853 Free PMC article.
Receptors for protons or lipid messengers or both?
Seuwen K, Ludwig MG, Wolf RM. Seuwen K, et al. J Recept Signal Transduct Res. 2006;26(5-6):599-610. doi: 10.1080/10799890600932220. J Recept Signal Transduct Res. 2006. PMID: 17118800 Review.
The proton-activated ovarian cancer G protein-coupled receptor 1 (OGR1) is responsible for renal calcium loss during acidosis.
Imenez Silva PH, Katamesh-Benabbas C, Chan K, Pastor Arroyo EM, Knöpfel T, Bettoni C, Ludwig MG, Gasser JA, Brandao-Burch A, Arnett TR, Bonny O, Seuwen K, Wagner CA. Imenez Silva PH, et al. Among authors: seuwen k. Kidney Int. 2020 May;97(5):920-933. doi: 10.1016/j.kint.2019.12.006. Epub 2019 Dec 25. Kidney Int. 2020. PMID: 32173037 Free article.
G Protein-coupled pH-sensing Receptor OGR1 Is a Regulator of Intestinal Inflammation.
de Vallière C, Wang Y, Eloranta JJ, Vidal S, Clay I, Spalinger MR, Tcymbarevich I, Terhalle A, Ludwig MG, Suply T, Fried M, Kullak-Ublick GA, Frey-Wagner I, Scharl M, Seuwen K, Wagner CA, Rogler G. de Vallière C, et al. Among authors: seuwen k. Inflamm Bowel Dis. 2015 Jun;21(6):1269-81. doi: 10.1097/MIB.0000000000000375. Inflamm Bowel Dis. 2015. PMID: 25856770 Free PMC article.
Proton-sensing G-protein-coupled receptors.
Ludwig MG, Vanek M, Guerini D, Gasser JA, Jones CE, Junker U, Hofstetter H, Wolf RM, Seuwen K. Ludwig MG, et al. Among authors: seuwen k. Nature. 2003 Sep 4;425(6953):93-8. doi: 10.1038/nature01905. Nature. 2003. PMID: 12955148
92 results