van Schendel R - Search Results

1

Polymerase Θ is a key driver of genome evolution and of CRISPR/Cas9-mediated mutagenesis.

van Schendel R, Roerink SF, Portegijs V, van den Heuvel S, Tijsterman M. van Schendel R, et al. Among authors: van den heuvel s. Nat Commun. 2015 Jun 16;6:7394. doi: 10.1038/ncomms8394. Nat Commun. 2015. PMID: 26077599 Free PMC article.

2

Microhomology-mediated intron loss during metazoan evolution.

van Schendel R, Tijsterman M. van Schendel R, et al. Genome Biol Evol. 2013;5(6):1212-9. doi: 10.1093/gbe/evt088. Genome Biol Evol. 2013. PMID: 23737326 Free PMC article.

3

A Polymerase Theta-dependent repair pathway suppresses extensive genomic instability at endogenous G4 DNA sites.

Koole W, van Schendel R, Karambelas AE, van Heteren JT, Okihara KL, Tijsterman M. Koole W, et al. Among authors: van heteren jt, van schendel r. Nat Commun. 2014;5:3216. doi: 10.1038/ncomms4216. Nat Commun. 2014. PMID: 24496117 Free article.

4

Polymerase theta-mediated end joining of replication-associated DNA breaks in C. elegans.

Roerink SF, van Schendel R, Tijsterman M. Roerink SF, et al. Among authors: van schendel r. Genome Res. 2014 Jun;24(6):954-62. doi: 10.1101/gr.170431.113. Epub 2014 Mar 10. Genome Res. 2014. PMID: 24614976 Free PMC article.

5

Mutagenic consequences of a single G-quadruplex demonstrate mitotic inheritance of DNA replication fork barriers.

Lemmens B, van Schendel R, Tijsterman M. Lemmens B, et al. Among authors: van schendel r. Nat Commun. 2015 Nov 13;6:8909. doi: 10.1038/ncomms9909. Nat Commun. 2015. PMID: 26563448 Free PMC article.

6

Histone H3K9 methylation is dispensable for Caenorhabditis elegans development but suppresses RNA:DNA hybrid-associated repeat instability.

Zeller P, Padeken J, van Schendel R, Kalck V, Tijsterman M, Gasser SM. Zeller P, et al. Among authors: van schendel r. Nat Genet. 2016 Nov;48(11):1385-1395. doi: 10.1038/ng.3672. Epub 2016 Sep 26. Nat Genet. 2016. PMID: 27668659

7

Genomic Scars Generated by Polymerase Theta Reveal the Versatile Mechanism of Alternative End-Joining.

van Schendel R, van Heteren J, Welten R, Tijsterman M. van Schendel R, et al. Among authors: van heteren j. PLoS Genet. 2016 Oct 18;12(10):e1006368. doi: 10.1371/journal.pgen.1006368. eCollection 2016 Oct. PLoS Genet. 2016. PMID: 27755535 Free PMC article.

8

T-DNA integration in plants results from polymerase-θ-mediated DNA repair.

van Kregten M, de Pater S, Romeijn R, van Schendel R, Hooykaas PJ, Tijsterman M. van Kregten M, et al. Among authors: van schendel r. Nat Plants. 2016 Oct 31;2(11):16164. doi: 10.1038/nplants.2016.164. Nat Plants. 2016. PMID: 27797358

9

Mutational signatures of non-homologous and polymerase theta-mediated end-joining in embryonic stem cells.

Schimmel J, Kool H, van Schendel R, Tijsterman M. Schimmel J, et al. Among authors: van schendel r. EMBO J. 2017 Dec 15;36(24):3634-3649. doi: 10.15252/embj.201796948. Epub 2017 Oct 27. EMBO J. 2017. PMID: 29079701 Free PMC article.

10

Templated Insertions: A Smoking Gun for Polymerase Theta-Mediated End Joining.

Schimmel J, van Schendel R, den Dunnen JT, Tijsterman M. Schimmel J, et al. Among authors: van schendel r. Trends Genet. 2019 Sep;35(9):632-644. doi: 10.1016/j.tig.2019.06.001. Epub 2019 Jul 8. Trends Genet. 2019. PMID: 31296341 Review.

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