Lai W - Search Results

1

A Decoy Peptide that Disrupts TIRAP Recruitment to TLRs Is Protective in a Murine Model of Influenza.

Piao W, Shirey KA, Ru LW, Lai W, Szmacinski H, Snyder GA, Sundberg EJ, Lakowicz JR, Vogel SN, Toshchakov VY. Piao W, et al. Among authors: lai w. Cell Rep. 2015 Jun 30;11(12):1941-52. doi: 10.1016/j.celrep.2015.05.035. Epub 2015 Jun 18. Cell Rep. 2015. PMID: 26095366 Free PMC article.

2

5,6-Dimethylxanthenone-4-acetic acid (DMXAA) activates stimulator of interferon gene (STING)-dependent innate immune pathways and is regulated by mitochondrial membrane potential.

Prantner D, Perkins DJ, Lai W, Williams MS, Sharma S, Fitzgerald KA, Vogel SN. Prantner D, et al. Among authors: lai w. J Biol Chem. 2012 Nov 16;287(47):39776-88. doi: 10.1074/jbc.M112.382986. Epub 2012 Oct 1. J Biol Chem. 2012. PMID: 23027866 Free PMC article.

3

The TLR4 antagonist Eritoran protects mice from lethal influenza infection.

Shirey KA, Lai W, Scott AJ, Lipsky M, Mistry P, Pletneva LM, Karp CL, McAlees J, Gioannini TL, Weiss J, Chen WH, Ernst RK, Rossignol DP, Gusovsky F, Blanco JC, Vogel SN. Shirey KA, et al. Among authors: lai w. Nature. 2013 May 23;497(7450):498-502. doi: 10.1038/nature12118. Epub 2013 May 1. Nature. 2013. PMID: 23636320 Free PMC article.

4

Reprogramming of murine macrophages through TLR2 confers viral resistance via TRAF3-mediated, enhanced interferon production.

Perkins DJ, Polumuri SK, Pennini ME, Lai W, Xie P, Vogel SN. Perkins DJ, et al. Among authors: lai w. PLoS Pathog. 2013;9(7):e1003479. doi: 10.1371/journal.ppat.1003479. Epub 2013 Jul 11. PLoS Pathog. 2013. PMID: 23853595 Free PMC article.

5

Role of the lipoxygenase pathway in RSV-induced alternatively activated macrophages leading to resolution of lung pathology.

Shirey KA, Lai W, Pletneva LM, Karp CL, Divanovic S, Blanco JC, Vogel SN. Shirey KA, et al. Among authors: lai w. Mucosal Immunol. 2014 May;7(3):549-57. doi: 10.1038/mi.2013.71. Epub 2013 Sep 25. Mucosal Immunol. 2014. PMID: 24064666 Free PMC article.

6

Agents that increase AAM differentiation blunt RSV-mediated lung pathology.

Shirey KA, Lai W, Pletneva LM, Finkelman FD, Feola DJ, Blanco JC, Vogel SN. Shirey KA, et al. Among authors: lai w. J Leukoc Biol. 2014 Dec;96(6):951-5. doi: 10.1189/jlb.4HI0414-226R. Epub 2014 Jul 9. J Leukoc Biol. 2014. PMID: 25009233 Free PMC article.

7

Novel strategies for targeting innate immune responses to influenza.

Shirey KA, Lai W, Patel MC, Pletneva LM, Pang C, Kurt-Jones E, Lipsky M, Roger T, Calandra T, Tracey KJ, Al-Abed Y, Bowie AG, Fasano A, Dinarello CA, Gusovsky F, Blanco JC, Vogel SN. Shirey KA, et al. Among authors: lai w. Mucosal Immunol. 2016 Sep;9(5):1173-82. doi: 10.1038/mi.2015.141. Epub 2016 Jan 27. Mucosal Immunol. 2016. PMID: 26813341 Free PMC article.

8

The θ-defensin retrocyclin 101 inhibits TLR4- and TLR2-dependent signaling and protects mice against influenza infection.

Prantner D, Shirey KA, Lai W, Lu W, Cole AM, Vogel SN, Garzino-Demo A. Prantner D, et al. Among authors: lai w. J Leukoc Biol. 2017 Oct;102(4):1103-1113. doi: 10.1189/jlb.2A1215-567RR. Epub 2017 Jul 20. J Leukoc Biol. 2017. PMID: 28729359 Free PMC article.

9

Novel role of gastrin releasing peptide-mediated signaling in the host response to influenza infection.

Shirey KA, Sunday ME, Lai W, Patel MC, Blanco JCG, Cuttitta F, Vogel SN. Shirey KA, et al. Among authors: lai w. Mucosal Immunol. 2019 Jan;12(1):223-231. doi: 10.1038/s41385-018-0081-9. Epub 2018 Oct 16. Mucosal Immunol. 2019. PMID: 30327535 Free PMC article.

10

Autocrine-paracrine prostaglandin E₂ signaling restricts TLR4 internalization and TRIF signaling.

Perkins DJ, Richard K, Hansen AM, Lai W, Nallar S, Koller B, Vogel SN. Perkins DJ, et al. Among authors: lai w. Nat Immunol. 2018 Dec;19(12):1309-1318. doi: 10.1038/s41590-018-0243-7. Epub 2018 Nov 5. Nat Immunol. 2018. PMID: 30397349 Free PMC article.

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