Tardiff J - Search Results

1

Synergistic role of ADP and Ca(2+) in diastolic myocardial stiffness.

Sequeira V, Najafi A, McConnell M, Fowler ED, Bollen IA, Wüst RC, dos Remedios C, Helmes M, White E, Stienen GJ, Tardiff J, Kuster DW, van der Velden J. Sequeira V, et al. Among authors: tardiff j. J Physiol. 2015 Sep 1;593(17):3899-916. doi: 10.1113/JP270354. Epub 2015 Jul 14. J Physiol. 2015. PMID: 26096258 Free PMC article.

2

The HCM - Linked Mutation Arg92Leu in TNNT2 Allosterically Alters the cTnC - cTnI Interface and Disrupts the PKA-mediated Regulation of Myofilament Relaxation.

Lynn ML, Jimenez J, Castillo RL, Klass MM, Vasquez C, Baldo A, Gibson C, Murphy AM, Tardiff JC. Lynn ML, et al. Among authors: tardiff jc. bioRxiv [Preprint]. 2023 Jul 19:2023.07.18.549569. doi: 10.1101/2023.07.18.549569. bioRxiv. 2023. PMID: 37503299 Free PMC article. Preprint.

3

Divergent Molecular Phenotypes in Point Mutations at the Same Residue in Beta-Myosin Heavy Chain Lead to Distinct Cardiomyopathies.

Lehman SJ, Meller A, Solieva SO, Lotthammer JM, Greenberg L, Langer SJ, Greenberg MJ, Tardiff JC, Bowman GR, Leinwand L. Lehman SJ, et al. Among authors: tardiff jc. bioRxiv [Preprint]. 2023 Jul 3:2023.07.03.547580. doi: 10.1101/2023.07.03.547580. bioRxiv. 2023. PMID: 37461648 Free PMC article. Preprint.

4

Cardiac troponin T mutations: correlation between the type of mutation and the nature of myofilament dysfunction in transgenic mice.

Montgomery DE, Tardiff JC, Chandra M. Montgomery DE, et al. Among authors: tardiff jc. J Physiol. 2001 Oct 15;536(Pt 2):583-92. doi: 10.1111/j.1469-7793.2001.0583c.xd. J Physiol. 2001. PMID: 11600691 Free PMC article.

5

Research priorities in sarcomeric cardiomyopathies.

van der Velden J, Ho CY, Tardiff JC, Olivotto I, Knollmann BC, Carrier L. van der Velden J, et al. Among authors: tardiff jc. Cardiovasc Res. 2015 Apr 1;105(4):449-56. doi: 10.1093/cvr/cvv019. Epub 2015 Jan 28. Cardiovasc Res. 2015. PMID: 25631582 Free PMC article. Review.

6

Targets for therapy in sarcomeric cardiomyopathies.

Tardiff JC, Carrier L, Bers DM, Poggesi C, Ferrantini C, Coppini R, Maier LS, Ashrafian H, Huke S, van der Velden J. Tardiff JC, et al. Cardiovasc Res. 2015 Apr 1;105(4):457-70. doi: 10.1093/cvr/cvv023. Epub 2015 Jan 29. Cardiovasc Res. 2015. PMID: 25634554 Free PMC article. Review.

7

Clinically Divergent Mutation Effects on the Structure and Function of the Human Cardiac Tropomyosin Overlap.

McConnell M, Tal Grinspan L, Williams MR, Lynn ML, Schwartz BA, Fass OZ, Schwartz SD, Tardiff JC. McConnell M, et al. Biochemistry. 2017 Jul 5;56(26):3403-3413. doi: 10.1021/acs.biochem.7b00266. Epub 2017 Jun 21. Biochemistry. 2017. PMID: 28603979 Free PMC article.

8

FRET-based analysis of the cardiac troponin T linker region reveals the structural basis of the hypertrophic cardiomyopathy-causing Δ160E mutation.

Abdullah S, Lynn ML, McConnell MT, Klass MM, Baldo AP, Schwartz SD, Tardiff JC. Abdullah S, et al. J Biol Chem. 2019 Oct 4;294(40):14634-14647. doi: 10.1074/jbc.RA118.005098. Epub 2019 Aug 6. J Biol Chem. 2019. PMID: 31387947 Free PMC article.

9

Sex-Related Differences in Genetic Cardiomyopathies.

Argirò A, Ho C, Day SM, van der Velden J, Cerbai E, Saberi S, Tardiff JC, Lakdawala NK, Olivotto I. Argirò A, et al. Among authors: tardiff jc. J Am Heart Assoc. 2022 May 3;11(9):e024947. doi: 10.1161/JAHA.121.024947. Epub 2022 Apr 26. J Am Heart Assoc. 2022. PMID: 35470690 Free PMC article. Review.

10

Ca(2+) activation of myofilaments from transgenic mouse hearts expressing R92Q mutant cardiac troponin T.

Chandra M, Rundell VL, Tardiff JC, Leinwand LA, De Tombe PP, Solaro RJ. Chandra M, et al. Among authors: tardiff jc. Am J Physiol Heart Circ Physiol. 2001 Feb;280(2):H705-13. doi: 10.1152/ajpheart.2001.280.2.H705. Am J Physiol Heart Circ Physiol. 2001. PMID: 11158969 Free article.

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