Willby M - Search Results

1

Correlation between GyrA substitutions and ofloxacin, levofloxacin, and moxifloxacin cross-resistance in Mycobacterium tuberculosis.

Willby M, Sikes RD, Malik S, Metchock B, Posey JE. Willby M, et al. Antimicrob Agents Chemother. 2015 Sep;59(9):5427-34. doi: 10.1128/AAC.00662-15. Epub 2015 Jun 22. Antimicrob Agents Chemother. 2015. PMID: 26100699 Free PMC article.

2

New insights into fluoroquinolone resistance in Mycobacterium tuberculosis: functional genetic analysis of gyrA and gyrB mutations.

Malik S, Willby M, Sikes D, Tsodikov OV, Posey JE. Malik S, et al. Among authors: willby m. PLoS One. 2012;7(6):e39754. doi: 10.1371/journal.pone.0039754. Epub 2012 Jun 28. PLoS One. 2012. PMID: 22761889 Free PMC article.

3

Antimycobacterial activity of DNA intercalator inhibitors of Mycobacterium tuberculosis primase DnaG.

Gajadeera C, Willby MJ, Green KD, Shaul P, Fridman M, Garneau-Tsodikova S, Posey JE, Tsodikov OV. Gajadeera C, et al. Among authors: willby mj. J Antibiot (Tokyo). 2015 Mar;68(3):153-7. doi: 10.1038/ja.2014.131. Epub 2014 Sep 24. J Antibiot (Tokyo). 2015. PMID: 25248725 Free PMC article.

4

Disparities in capreomycin resistance levels associated with the rrs A1401G mutation in clinical isolates of Mycobacterium tuberculosis.

Reeves AZ, Campbell PJ, Willby MJ, Posey JE. Reeves AZ, et al. Antimicrob Agents Chemother. 2015 Jan;59(1):444-9. doi: 10.1128/AAC.04438-14. Epub 2014 Nov 10. Antimicrob Agents Chemother. 2015. PMID: 25385119 Free PMC article.

5

Mycobacterium tuberculosis pncA Polymorphisms That Do Not Confer Pyrazinamide Resistance at a Breakpoint Concentration of 100 Micrograms per Milliliter in MGIT.

Whitfield MG, Warren RM, Streicher EM, Sampson SL, Sirgel FA, van Helden PD, Mercante A, Willby M, Hughes K, Birkness K, Morlock G, van Rie A, Posey JE. Whitfield MG, et al. Among authors: willby m. J Clin Microbiol. 2015 Nov;53(11):3633-5. doi: 10.1128/JCM.01001-15. Epub 2015 Aug 19. J Clin Microbiol. 2015. PMID: 26292310 Free PMC article.

6

Rv3351c, a Mycobacterium tuberculosis gene that affects bacterial growth and alveolar epithelial cell viability.

Pavlicek RL, Fine-Coulson K, Gupta T, Quinn FD, Posey JE, Willby M, Castro-Garza J, Karls RK. Pavlicek RL, et al. Among authors: willby m. Can J Microbiol. 2015 Dec;61(12):938-47. doi: 10.1139/cjm-2015-0528. Epub 2015 Oct 22. Can J Microbiol. 2015. PMID: 26492080

7

Potent Inhibitors of Acetyltransferase Eis Overcome Kanamycin Resistance in Mycobacterium tuberculosis.

Willby MJ, Green KD, Gajadeera CS, Hou C, Tsodikov OV, Posey JE, Garneau-Tsodikova S. Willby MJ, et al. ACS Chem Biol. 2016 Jun 17;11(6):1639-46. doi: 10.1021/acschembio.6b00110. Epub 2016 Apr 7. ACS Chem Biol. 2016. PMID: 27010218 Free PMC article.

8

Sulfonamide-Based Inhibitors of Aminoglycoside Acetyltransferase Eis Abolish Resistance to Kanamycin in Mycobacterium tuberculosis.

Garzan A, Willby MJ, Green KD, Gajadeera CS, Hou C, Tsodikov OV, Posey JE, Garneau-Tsodikova S. Garzan A, et al. J Med Chem. 2016 Dec 8;59(23):10619-10628. doi: 10.1021/acs.jmedchem.6b01161. Epub 2016 Nov 22. J Med Chem. 2016. PMID: 27933949 Free PMC article.

9

Discovery and Optimization of Two Eis Inhibitor Families as Kanamycin Adjuvants against Drug-Resistant M. tuberculosis.

Garzan A, Willby MJ, Green KD, Tsodikov OV, Posey JE, Garneau-Tsodikova S. Garzan A, et al. ACS Med Chem Lett. 2016 Sep 15;7(12):1219-1221. doi: 10.1021/acsmedchemlett.6b00261. eCollection 2016 Dec 8. ACS Med Chem Lett. 2016. PMID: 27994767 Free PMC article.

10

Combating Enhanced Intracellular Survival (Eis)-Mediated Kanamycin Resistance of Mycobacterium tuberculosis by Novel Pyrrolo[1,5-a]pyrazine-Based Eis Inhibitors.

Garzan A, Willby MJ, Ngo HX, Gajadeera CS, Green KD, Holbrook SY, Hou C, Posey JE, Tsodikov OV, Garneau-Tsodikova S. Garzan A, et al. ACS Infect Dis. 2017 Apr 14;3(4):302-309. doi: 10.1021/acsinfecdis.6b00193. Epub 2017 Feb 17. ACS Infect Dis. 2017. PMID: 28192916 Free PMC article.

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