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1,395 results

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Rare coding mutations identified by sequencing of Alzheimer disease genome-wide association studies loci.
Vardarajan BN, Ghani M, Kahn A, Sheikh S, Sato C, Barral S, Lee JH, Cheng R, Reitz C, Lantigua R, Reyes-Dumeyer D, Medrano M, Jimenez-Velazquez IZ, Rogaeva E, St George-Hyslop P, Mayeux R. Vardarajan BN, et al. Among authors: sato c. Ann Neurol. 2015 Sep;78(3):487-98. doi: 10.1002/ana.24466. Epub 2015 Jul 28. Ann Neurol. 2015. PMID: 26101835 Free PMC article.
Association between angiotensin-converting enzyme and Alzheimer disease.
Farrer LA, Sherbatich T, Keryanov SA, Korovaitseva GI, Rogaeva EA, Petruk S, Premkumar S, Moliaka Y, Song YQ, Pei Y, Sato C, Selezneva ND, Voskresenskaya S, Golimbet V, Sorbi S, Duara R, Gavrilova S, St George-Hyslop PH, Rogaev EI. Farrer LA, et al. Among authors: sato c. Arch Neurol. 2000 Feb;57(2):210-4. doi: 10.1001/archneur.57.2.210. Arch Neurol. 2000. PMID: 10681079 Clinical Trial.
Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and betaAPP processing.
Yu G, Nishimura M, Arawaka S, Levitan D, Zhang L, Tandon A, Song YQ, Rogaeva E, Chen F, Kawarai T, Supala A, Levesque L, Yu H, Yang DS, Holmes E, Milman P, Liang Y, Zhang DM, Xu DH, Sato C, Rogaev E, Smith M, Janus C, Zhang Y, Aebersold R, Farrer LS, Sorbi S, Bruni A, Fraser P, St George-Hyslop P. Yu G, et al. Among authors: sato c. Nature. 2000 Sep 7;407(6800):48-54. doi: 10.1038/35024009. Nature. 2000. PMID: 10993067
Mutation of the conserved N-terminal cysteine (Cys92) of human presenilin 1 causes increased A beta42 secretion in mammalian cells but impaired Notch/lin-12 signalling in C. elegans.
Zhang DM, Levitan D, Yu G, Nishimura M, Chen F, Tandon A, Kawarai T, Arawaka S, Supala A, Song YQ, Rogaeva E, Liang Y, Holmes E, Milman P, Sato C, Zhang L, St George-Hyslop P. Zhang DM, et al. Among authors: sato c. Neuroreport. 2000 Sep 28;11(14):3227-30. doi: 10.1097/00001756-200009280-00035. Neuroreport. 2000. PMID: 11043553
Nicastrin binds to membrane-tethered Notch.
Chen F, Yu G, Arawaka S, Nishimura M, Kawarai T, Yu H, Tandon A, Supala A, Song YQ, Rogaeva E, Milman P, Sato C, Yu C, Janus C, Lee J, Song L, Zhang L, Fraser PE, St George-Hyslop PH. Chen F, et al. Among authors: sato c. Nat Cell Biol. 2001 Aug;3(8):751-4. doi: 10.1038/35087069. Nat Cell Biol. 2001. PMID: 11483961
A founder mutation in presenilin 1 causing early-onset Alzheimer disease in unrelated Caribbean Hispanic families.
Athan ES, Williamson J, Ciappa A, Santana V, Romas SN, Lee JH, Rondon H, Lantigua RA, Medrano M, Torres M, Arawaka S, Rogaeva E, Song YQ, Sato C, Kawarai T, Fafel KC, Boss MA, Seltzer WK, Stern Y, St George-Hyslop P, Tycko B, Mayeux R. Athan ES, et al. Among authors: sato c. JAMA. 2001 Nov 14;286(18):2257-63. doi: 10.1001/jama.286.18.2257. JAMA. 2001. PMID: 11710891
Mutations in the open reading frame of the beta-site APP cleaving enzyme (BACE) locus are not a common cause of Alzheimer's disease.
Nicolaou M, Song YQ, Sato CA, Orlacchio A, Kawarai T, Medeiros H, Liang Y, Sorbi S, Richard E, Rogaev EI, Moliaka Y, Bruni AC, Jorge R, Percy M, Duara R, Farrer LA, St Georg-Hyslop P, Rogaeva EA. Nicolaou M, et al. Among authors: sato ca. Neurogenetics. 2001 Oct;3(4):203-6. doi: 10.1007/s100480100123. Neurogenetics. 2001. PMID: 11714100
1,395 results