Liang SC - Search Results

1

In Vitro Evaluation of the Effect of 7-Methyl Substitution on Glucuronidation of Daphnetin: Metabolic Stability, Isoform Selectivity, and Bioactivity Analysis.

Liang SC, Ge GB, Xia YL, Zhang JW, Qi XY, Tu CX, Yang L. Liang SC, et al. J Pharm Sci. 2015 Oct;104(10):3557-64. doi: 10.1002/jps.24538. Epub 2015 Jun 17. J Pharm Sci. 2015. PMID: 26104686

2

Identification and characterization of human UDP-glucuronosyltransferases responsible for the in vitro glucuronidation of daphnetin.

Liang SC, Ge GB, Liu HX, Zhang YY, Wang LM, Zhang JW, Yin L, Li W, Fang ZZ, Wu JJ, Li GH, Yang L. Liang SC, et al. Drug Metab Dispos. 2010 Jun;38(6):973-80. doi: 10.1124/dmd.109.030734. Epub 2010 Feb 22. Drug Metab Dispos. 2010. PMID: 20176691

3

Determination of propofol UDP-glucuronosyltransferase (UGT) activities in hepatic microsomes from different species by UFLC-ESI-MS.

Liang SC, Ge GB, Liu HX, Shang HT, Wei H, Fang ZZ, Zhu LL, Mao YX, Yang L. Liang SC, et al. J Pharm Biomed Anal. 2011 Jan 5;54(1):236-41. doi: 10.1016/j.jpba.2010.07.049. Epub 2010 Aug 13. J Pharm Biomed Anal. 2011. PMID: 20828969

4

The role of serum albumin in the metabolism of Boc5: molecular identification, species differences and contribution to plasma metabolism.

Ge GB, Ai CZ, Hu WB, Hou J, Zhu LL, He GY, Fang ZZ, Liang SC, Wang FY, Yang L. Ge GB, et al. Among authors: liang sc. Eur J Pharm Sci. 2013 Jan 23;48(1-2):360-9. doi: 10.1016/j.ejps.2012.11.011. Epub 2012 Dec 6. Eur J Pharm Sci. 2013. PMID: 23220486

5

Identification and characterization of human UDP-glucuronosyltransferases responsible for the glucuronidation of fraxetin.

Xia YL, Liang SC, Zhu LL, Ge GB, He GY, Ning J, Lv X, Ma XC, Yang L, Yang SL. Xia YL, et al. Among authors: liang sc. Drug Metab Pharmacokinet. 2014;29(2):135-40. doi: 10.2133/dmpk.dmpk-13-rg-059. Epub 2013 Sep 10. Drug Metab Pharmacokinet. 2014. PMID: 24025985 Free article.

6

Structural modifications at the C-4 position strongly affect the glucuronidation of 6,7-dihydroxycoumarins.

Xia YL, Ge GB, Wang P, Liang SC, He YQ, Ning J, Qian XK, Li Y, Yang L. Xia YL, et al. Among authors: liang sc. Drug Metab Dispos. 2015 Apr;43(4):553-60. doi: 10.1124/dmd.114.060681. Epub 2015 Jan 27. Drug Metab Dispos. 2015. PMID: 25626951 Free article.

7

Methylation, Glucuronidation, and Sulfonation of Daphnetin in Human Hepatic Preparations In Vitro: Metabolic Profiling, Pathway Comparison, and Bioactivity Analysis.

Liang SC, Xia YL, Hou J, Ge GB, Zhang JW, He YQ, Wang JY, Qi XY, Yang L. Liang SC, et al. J Pharm Sci. 2016 Feb;105(2):808-816. doi: 10.1016/j.xphs.2015.10.010. Epub 2016 Jan 6. J Pharm Sci. 2016. PMID: 26869431

8

Inhibition of human catechol-O-methyltransferase-mediated dopamine O-methylation by daphnetin and its Phase II metabolites.

Liang SC, Ge GB, Xia YL, Pei-Pei D, Ping W, Qi XY, Cai-Xia T, Ling Y. Liang SC, et al. Xenobiotica. 2017 Jun;47(6):498-504. doi: 10.1080/00498254.2016.1204567. Epub 2016 Jul 20. Xenobiotica. 2017. PMID: 27435571

9

Characterization of hepatic and intestinal glucuronidation of magnolol: application of the relative activity factor approach to decipher the contributions of multiple UDP-glucuronosyltransferase isoforms.

Zhu L, Ge G, Zhang H, Liu H, He G, Liang S, Zhang Y, Fang Z, Dong P, Finel M, Yang L. Zhu L, et al. Drug Metab Dispos. 2012 Mar;40(3):529-38. doi: 10.1124/dmd.111.042192. Epub 2011 Dec 16. Drug Metab Dispos. 2012. PMID: 22180045

10

Potent and selective inhibition of magnolol on catalytic activities of UGT1A7 and 1A9.

Zhu L, Ge G, Liu Y, He G, Liang S, Fang Z, Dong P, Cao Y, Yang L. Zhu L, et al. Xenobiotica. 2012 Oct;42(10):1001-8. doi: 10.3109/00498254.2012.681814. Epub 2012 May 16. Xenobiotica. 2012. PMID: 22591254

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