Tanaka E - Search Results

1

Simplified approach for determination of hepatic drug-oxidizing capacity using trimethadione metabolism as an indicator.

Tanaka E, Kobayashi S, Nakamura K, Uchida E, Yasuhara H. Tanaka E, et al. Biopharm Drug Dispos. 1989 Nov-Dec;10(6):617-20. doi: 10.1002/bdd.2510100611. Biopharm Drug Dispos. 1989. PMID: 2611361 Clinical Trial. No abstract available.

2

Trimethadione metabolism as a probe drug to estimate hepatic oxidizing capacity in rats.

Tanaka E, Ishikawa A, Kobayashi S, Yasuhara H, Misawa S, Kuroiwa Y. Tanaka E, et al. Comp Biochem Physiol C Comp Pharmacol Toxicol. 1993 Feb;104(2):205-7. doi: 10.1016/0742-8413(93)90025-g. Comp Biochem Physiol C Comp Pharmacol Toxicol. 1993. PMID: 8098675 Review.

3

Trimethadione as a probe drug to estimate hepatic oxidizing capacity in humans.

Tanaka E, Ishikawa A, Abei M, Kobayashi S. Tanaka E, et al. Comp Biochem Physiol C Pharmacol Toxicol Endocrinol. 1996 Nov;115(3):211-6. doi: 10.1016/s0742-8413(96)00102-8. Comp Biochem Physiol C Pharmacol Toxicol Endocrinol. 1996. PMID: 9375358 Review.

4

Strain differences of antipyrine, trimethadione, and debrisoquine metabolism in female rats.

Tanaka E, Kobayashi S, Yasuhara H, Misawa S. Tanaka E, et al. Res Commun Chem Pathol Pharmacol. 1990 Aug;69(2):233-6. Res Commun Chem Pathol Pharmacol. 1990. PMID: 2396050 No abstract available.

5

Comparison of trimethadione and antipyrine as indicators of oxidative drug metabolizing capacity in man.

Tanaka E, Nakamura K. Tanaka E, et al. Eur J Clin Pharmacol. 1989;36(6):629-32. doi: 10.1007/BF00637749. Eur J Clin Pharmacol. 1989. PMID: 2776822

6

A simplified approach for evaluation of hepatic drug-oxidizing activity with a simultaneous determination of caffeine and trimethadione and their demethylated metabolites in rats with a selective cytochrome P-450 inducer.

Tanaka E, Ishikawa A, Yamamoto Y, Uchida E, Kobayashi S, Yasuhara H, Misawa S. Tanaka E, et al. Biopharm Drug Dispos. 1992 May;13(4):263-72. doi: 10.1002/bdd.2510130405. Biopharm Drug Dispos. 1992. PMID: 1600112

7

Simplified approach for evaluation of hepatic drug-oxidizing capacity with a simultaneous measurement of caffeine and its primary demethylated metabolites in carbon tetrachloride-intoxicated rats.

Tanaka E, Ishikawa A, Yamamoto Y, Uchida E, Kobayashi S, Yasuhara H, Misawa S. Tanaka E, et al. Xenobiotica. 1992 May;22(5):535-41. doi: 10.3109/00498259209053116. Xenobiotica. 1992. PMID: 1413868

8

How useful is the "cocktail approach" for evaluating human hepatic drug metabolizing capacity using cytochrome P450 phenotyping probes in vivo?

Tanaka E, Kurata N, Yasuhara H. Tanaka E, et al. J Clin Pharm Ther. 2003 Jun;28(3):157-65. doi: 10.1046/j.1365-2710.2003.00486.x. J Clin Pharm Ther. 2003. PMID: 12795773 Review.

9

Involvement of cytochrome P450 2C9, 2E1 and 3A4 in trimethadione N-demethylation in human microsomes.

Tanaka E, Kurata N, Yasuhara H. Tanaka E, et al. J Clin Pharm Ther. 2003 Dec;28(6):493-6. doi: 10.1046/j.1365-2710.2003.00524.x. J Clin Pharm Ther. 2003. PMID: 14651673

10

Antipyrine metabolism in female Lewis and Dark Agouti strains of rats, which are extensive and poor metabolizers of debrisoquine, respectively.

Tanaka E, Kobayashi S, Uchida E, Oguchi K, Yasuhara H. Tanaka E, et al. Jpn J Pharmacol. 1989 Mar;49(3):433-5. doi: 10.1254/jjp.49.433. Jpn J Pharmacol. 1989. PMID: 2747044 Free article.

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