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O-glycans direct selectin ligands to lipid rafts on leukocytes.
Shao B, Yago T, Setiadi H, Wang Y, Mehta-D'souza P, Fu J, Crocker PR, Rodgers W, Xia L, McEver RP. Shao B, et al. Among authors: fu j. Proc Natl Acad Sci U S A. 2015 Jul 14;112(28):8661-6. doi: 10.1073/pnas.1507712112. Epub 2015 Jun 29. Proc Natl Acad Sci U S A. 2015. PMID: 26124096 Free PMC article.
Loss of intestinal core 1-derived O-glycans causes spontaneous colitis in mice.
Fu J, Wei B, Wen T, Johansson ME, Liu X, Bradford E, Thomsson KA, McGee S, Mansour L, Tong M, McDaniel JM, Sferra TJ, Turner JR, Chen H, Hansson GC, Braun J, Xia L. Fu J, et al. J Clin Invest. 2011 Apr;121(4):1657-66. doi: 10.1172/JCI45538. Epub 2011 Mar 7. J Clin Invest. 2011. PMID: 21383503 Free PMC article.
Podoplanin maintains high endothelial venule integrity by interacting with platelet CLEC-2.
Herzog BH, Fu J, Wilson SJ, Hess PR, Sen A, McDaniel JM, Pan Y, Sheng M, Yago T, Silasi-Mansat R, McGee S, May F, Nieswandt B, Morris AJ, Lupu F, Coughlin SR, McEver RP, Chen H, Kahn ML, Xia L. Herzog BH, et al. Among authors: fu j. Nature. 2013 Oct 3;502(7469):105-9. doi: 10.1038/nature12501. Epub 2013 Sep 1. Nature. 2013. PMID: 23995678 Free PMC article.
The CLEC-2-podoplanin axis controls the contractility of fibroblastic reticular cells and lymph node microarchitecture.
Astarita JL, Cremasco V, Fu J, Darnell MC, Peck JR, Nieves-Bonilla JM, Song K, Kondo Y, Woodruff MC, Gogineni A, Onder L, Ludewig B, Weimer RM, Carroll MC, Mooney DJ, Xia L, Turley SJ. Astarita JL, et al. Among authors: fu j. Nat Immunol. 2015 Jan;16(1):75-84. doi: 10.1038/ni.3035. Epub 2014 Oct 27. Nat Immunol. 2015. PMID: 25347465 Free PMC article.
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