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A novel small molecule, (E)-5-(2,4-di-tert-butyl-6-((2,4-dioxothiazolidin-5-ylidene)methyl)phenyl)-5'-methyl-7,7'-dimethoxy-4,4'-bibenzo[d][1,3]dioxole-5,5'-dicarboxylate (7k), alleviates the development of D-galactosamine/lipopolysaccharide-induced acute liver failure by inhibiting macrophage infiltration and regulating cytokine expression.
Deng C, Liu J, Wang G, Ma L, Xie C, Wang X, Li X, Chen L. Deng C, et al. Among authors: liu j. J Pharmacol Exp Ther. 2012 Apr;341(1):146-55. doi: 10.1124/jpet.111.189498. Epub 2012 Jan 11. J Pharmacol Exp Ther. 2012. PMID: 22238210
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