Wu JJ - Search Results

1

A Mechanism-Based Model for the Prediction of the Metabolic Sites of Steroids Mediated by Cytochrome P450 3A4.

Dai ZR, Ai CZ, Ge GB, He YQ, Wu JJ, Wang JY, Man HZ, Jia Y, Yang L. Dai ZR, et al. Among authors: wu jj. Int J Mol Sci. 2015 Jun 30;16(7):14677-94. doi: 10.3390/ijms160714677. Int J Mol Sci. 2015. PMID: 26133240 Free PMC article.

2

Gomisin A is a Novel Isoform-Specific Probe for the Selective Sensing of Human Cytochrome P450 3A4 in Liver Microsomes and Living Cells.

Wu JJ, Ge GB, He YQ, Wang P, Dai ZR, Ning J, Hu LH, Yang L. Wu JJ, et al. AAPS J. 2016 Jan;18(1):134-45. doi: 10.1208/s12248-015-9827-4. Epub 2015 Sep 11. AAPS J. 2016. PMID: 26361765 Free PMC article.

3

Interactions between phytochemicals from traditional Chinese medicines and human cytochrome P450 enzymes.

Wu JJ, Ai CZ, Liu Y, Zhang YY, Jiang M, Fan XR, Lv AP, Yang L. Wu JJ, et al. Curr Drug Metab. 2012 Jun 1;13(5):599-614. doi: 10.2174/1389200211209050599. Curr Drug Metab. 2012. PMID: 22475333 Review.

4

Characterization of phase I metabolism of resibufogenin and evaluation of the metabolic effects on its antitumor activity and toxicity.

Ning J, Yu ZL, Hu LH, Wang C, Huo XK, Deng S, Hou J, Wu JJ, Ge GB, Ma XC, Yang L. Ning J, et al. Among authors: wu jj. Drug Metab Dispos. 2015 Mar;43(3):299-308. doi: 10.1124/dmd.114.060996. Epub 2014 Dec 11. Drug Metab Dispos. 2015. PMID: 25504504

5

Interspecies variation in phase I metabolism of bufalin in hepatic microsomes from mouse, rat, dog, minipig, monkey, and human.

Ning J, Hou J, Wang P, Wu JJ, Dai ZR, Zou LW, Li W, Ge GB, Ma XC, Yang L. Ning J, et al. Among authors: wu jj. Xenobiotica. 2015;45(11):954-60. doi: 10.3109/00498254.2015.1035359. Epub 2015 Jun 8. Xenobiotica. 2015. PMID: 26053559

6

Inhibition of human cytochrome P450 enzymes by licochalcone A, a naturally occurring constituent of licorice.

He W, Wu JJ, Ning J, Hou J, Xin H, He YQ, Ge GB, Xu W. He W, et al. Among authors: wu jj. Toxicol In Vitro. 2015 Oct;29(7):1569-76. doi: 10.1016/j.tiv.2015.06.014. Epub 2015 Jun 19. Toxicol In Vitro. 2015. PMID: 26100226

7

A Naturally Occurring Isoform-Specific Probe for Highly Selective and Sensitive Detection of Human Cytochrome P450 3A5.

Wu JJ, Cao YF, Feng L, He YQ, Hong JY, Dou TY, Wang P, Hao DC, Ge GB, Yang L. Wu JJ, et al. J Med Chem. 2017 May 11;60(9):3804-3813. doi: 10.1021/acs.jmedchem.7b00001. Epub 2017 May 1. J Med Chem. 2017. PMID: 28441491

8

Cytochrome P450 3A Enzymes Are Key Contributors for Hepatic Metabolism of Bufotalin, a Natural Constitute in Chinese Medicine Chansu.

Dai ZR, Ning J, Sun GB, Wang P, Zhang F, Ma HY, Zou LW, Hou J, Wu JJ, Ge GB, Sun XB, Yang L. Dai ZR, et al. Among authors: wu jj. Front Pharmacol. 2019 Feb 4;10:52. doi: 10.3389/fphar.2019.00052. eCollection 2019. Front Pharmacol. 2019. PMID: 30778299 Free PMC article.

9

Identification and characterization of human UDP-glucuronosyltransferases responsible for the in vitro glucuronidation of daphnetin.

Liang SC, Ge GB, Liu HX, Zhang YY, Wang LM, Zhang JW, Yin L, Li W, Fang ZZ, Wu JJ, Li GH, Yang L. Liang SC, et al. Among authors: wu jj. Drug Metab Dispos. 2010 Jun;38(6):973-80. doi: 10.1124/dmd.109.030734. Epub 2010 Feb 22. Drug Metab Dispos. 2010. PMID: 20176691

10

Assessment of the inhibition potential of Licochalcone A against human UDP-glucuronosyltransferases.

Xin H, Qi XY, Wu JJ, Wang XX, Li Y, Hong JY, He W, Xu W, Ge GB, Yang L. Xin H, et al. Among authors: wu jj. Food Chem Toxicol. 2016 Apr;90:112-22. doi: 10.1016/j.fct.2016.02.007. Epub 2016 Feb 10. Food Chem Toxicol. 2016. PMID: 26875642

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