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Tenofovir 1% vaginal gel for prevention of HIV-1 infection in women in South Africa (FACTS-001): a phase 3, randomised, double-blind, placebo-controlled trial.
Delany-Moretlwe S, Lombard C, Baron D, Bekker LG, Nkala B, Ahmed K, Sebe M, Brumskine W, Nchabeleng M, Palanee-Philips T, Ntshangase J, Sibiya S, Smith E, Panchia R, Myer L, Schwartz JL, Marzinke M, Morris L, Brown ER, Doncel GF, Gray G, Rees H. Delany-Moretlwe S, et al. Among authors: smith e. Lancet Infect Dis. 2018 Nov;18(11):1241-1250. doi: 10.1016/S1473-3099(18)30428-6. Epub 2018 Oct 24. Lancet Infect Dis. 2018. PMID: 30507409 Clinical Trial.
Pathobiont-triggered induction of epithelial IDO1 drives regional susceptibility to Inflammatory Bowel Disease.
Spencer PN, Wang J, Smith EP, Spiga L, Simmons AJ, Kim T, Kim W, Brown ME, Yang Y, Kaur H, Xu Y, Kang SW, Helou MD, Lee MA, Zheng L, Arceneaux D, Tasneem N, Mueller KD, Kuddar OS, Harned MH, Ro J, Li J, Banerjee A, Markham NO, Wilson KT, Coburn LA, Goettel JA, Liu Q, Washington MK, Valdivia RH, Zhu W, Lau KS. Spencer PN, et al. Among authors: smith ep. bioRxiv [Preprint]. 2025 Jan 4:2025.01.04.630951. doi: 10.1101/2025.01.04.630951. bioRxiv. 2025. PMID: 39803424 Free PMC article. Preprint.
An Overview of Patient-reported Outcomes for Men with Prostate Cancer: Results from the PIONEER Consortium.
Remmers S, Beyer K, Lalmahomed TA, Prinsen P, Horevoorts NJE, Sibert NT, Kowalski C, Barletta F, Brunckhorst O, Gandaglia G, van der Voort van Zyp JRN, Smith EJ, Deschamps A, Collette L, Cornford P, Evans-Axelsson S, N'Dow J, Hemelrijck MV, Roobol MJ, Venderbos LDF; PIONEER Consortium. Remmers S, et al. Among authors: smith ej. Eur Urol Open Sci. 2024 Dec 17;71:106-113. doi: 10.1016/j.euros.2024.11.009. eCollection 2025 Jan. Eur Urol Open Sci. 2024. PMID: 39801658 Free PMC article.
Blarcamesine for the treatment of Early Alzheimer's Disease: Results from the ANAVEX2-73-AD-004 Phase IIB/III trial.
Macfarlane S, Grimmer T, Teo K, O'Brien TJ, Woodward M, Grunfeld J, Mander A, Brodtmann A, Brew BJ, Morris P, Short C, Kurrle S, Lai R, Bharadwaj S, Drysdale P, Sturm J, Lewis SJG, Barton D, Kalafatis C, Sharif S, Perry R, Mannering N, MacSweeney JE, Pearson S, Evans C, Krishna V, Thompson A, Munisamy M, Bhatt N, Asher A, Connell S, Lynch J, Rutgers SM, Dautzenberg PL, Prins N, Oschmann P, Frölich L, Tacik P, Peters O, Wiltfang J, Henri-Bhargava A, Smith E, Pasternak S, Frank A, Chertkow H, Ingram J, Hsiung GR, Brittain R, Tartaglia C, Cohen S, Villa LM, Gordon E, Jubault T, Guizard N, Tucker A, Kaufmann WE, Jin K, Chezem WR, Missling CU, Sabbagh MN. Macfarlane S, et al. Among authors: smith e. J Prev Alzheimers Dis. 2025 Jan;12(1):100016. doi: 10.1016/j.tjpad.2024.100016. Epub 2025 Jan 1. J Prev Alzheimers Dis. 2025. PMID: 39800452 Clinical Trial.
Covert Vascular Brain Injury and Cognitive Dysfunction Among Chinese Adults Living in Canada and China: The CAHHM and PURE-MIND Studies.
Ke C, Anand SS, Smith EE, Schulze KM, Moody A, Lear S, Poirier P, Dummer T, Desai D, Thayalasuthan V, Yusuf S, Teo KK, Wielgosz A, Lee D; as the Canadian Alliance of Healthy Hearts and Minds (CAHHM) and the Prospective Urban Rural Epidemiological (PURE) Study Investigators. Ke C, et al. Among authors: smith ee. Neurology. 2025 Feb 11;104(3):e210246. doi: 10.1212/WNL.0000000000210246. Epub 2025 Jan 9. Neurology. 2025. PMID: 39787476
TAK-994 Mechanistic Investigation into Drug-Induced Liver Injury.
Shinozawa T, Miyamoto K, Baker KS, Faber SC, Flores R, Uetrecht J, von Hehn C, Yukawa T, Tohyama K, Kadali H, von Grotthuss M, Sudo Y, Smith EN, Diogo D, Zhu AZX, Dragan Y, Cebers G, Wagoner MP. Shinozawa T, et al. Among authors: smith en. Toxicol Sci. 2025 Jan 9:kfaf003. doi: 10.1093/toxsci/kfaf003. Online ahead of print. Toxicol Sci. 2025. PMID: 39786842
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