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Remote control of neuronal activity with a light-gated glutamate receptor.
Szobota S, Gorostiza P, Del Bene F, Wyart C, Fortin DL, Kolstad KD, Tulyathan O, Volgraf M, Numano R, Aaron HL, Scott EK, Kramer RH, Flannery J, Baier H, Trauner D, Isacoff EY. Szobota S, et al. Among authors: isacoff ey. Neuron. 2007 May 24;54(4):535-45. doi: 10.1016/j.neuron.2007.05.010. Neuron. 2007. PMID: 17521567 Free article.
LiGluR restores visual responses in rodent models of inherited blindness.
Caporale N, Kolstad KD, Lee T, Tochitsky I, Dalkara D, Trauner D, Kramer R, Dan Y, Isacoff EY, Flannery JG. Caporale N, et al. Among authors: isacoff ey. Mol Ther. 2011 Jul;19(7):1212-9. doi: 10.1038/mt.2011.103. Epub 2011 May 24. Mol Ther. 2011. PMID: 21610698 Free PMC article.
Optical control of metabotropic glutamate receptors.
Levitz J, Pantoja C, Gaub B, Janovjak H, Reiner A, Hoagland A, Schoppik D, Kane B, Stawski P, Schier AF, Trauner D, Isacoff EY. Levitz J, et al. Among authors: isacoff ey. Nat Neurosci. 2013 Apr;16(4):507-16. doi: 10.1038/nn.3346. Epub 2013 Mar 3. Nat Neurosci. 2013. PMID: 23455609 Free PMC article.
Restoration of visual function by expression of a light-gated mammalian ion channel in retinal ganglion cells or ON-bipolar cells.
Gaub BM, Berry MH, Holt AE, Reiner A, Kienzler MA, Dolgova N, Nikonov S, Aguirre GD, Beltran WA, Flannery JG, Isacoff EY. Gaub BM, et al. Among authors: isacoff ey. Proc Natl Acad Sci U S A. 2014 Dec 23;111(51):E5574-83. doi: 10.1073/pnas.1414162111. Epub 2014 Dec 8. Proc Natl Acad Sci U S A. 2014. PMID: 25489083 Free PMC article.
Restoring Vision to the Blind with Chemical Photoswitches.
Tochitsky I, Kienzler MA, Isacoff E, Kramer RH. Tochitsky I, et al. Chem Rev. 2018 Nov 14;118(21):10748-10773. doi: 10.1021/acs.chemrev.7b00723. Epub 2018 Jun 6. Chem Rev. 2018. PMID: 29874052 Free PMC article. Review.
Restoration of high-sensitivity and adapting vision with a cone opsin.
Berry MH, Holt A, Salari A, Veit J, Visel M, Levitz J, Aghi K, Gaub BM, Sivyer B, Flannery JG, Isacoff EY. Berry MH, et al. Among authors: isacoff ey. Nat Commun. 2019 Mar 15;10(1):1221. doi: 10.1038/s41467-019-09124-x. Nat Commun. 2019. PMID: 30874546 Free PMC article.
193 results