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The Histone Methyltransferase Inhibitor A-366 Uncovers a Role for G9a/GLP in the Epigenetics of Leukemia.
PLoS One. 2015 Jul 6;10(7):e0131716. doi: 10.1371/journal.pone.0131716. eCollection 2015.
PLoS One. 2015.
PMID: 26147105
Free PMC article.
A win-win solution in oral delivery of lipophilic drugs: supersaturation via amorphous solid dispersions increases apparent solubility without sacrifice of intestinal membrane permeability.
Miller JM, Beig A, Carr RA, Spence JK, Dahan A.
Miller JM, et al. Among authors: spence jk.
Mol Pharm. 2012 Jul 2;9(7):2009-16. doi: 10.1021/mp300104s. Epub 2012 Jun 20.
Mol Pharm. 2012.
PMID: 22632106
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A pH-dilution method for estimation of biorelevant drug solubility along the gastrointestinal tract: application to physiologically based pharmacokinetic modeling.
Gao Y, Carr RA, Spence JK, Wang WW, Turner TM, Lipari JM, Miller JM.
Gao Y, et al. Among authors: spence jk.
Mol Pharm. 2010 Oct 4;7(5):1516-26. doi: 10.1021/mp100157s. Epub 2010 Aug 17.
Mol Pharm. 2010.
PMID: 20715778
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Increased dissolution rate and bioavailability through comicronization with microcrystalline cellulose.
Spence JK, Bhattachar SN, Wesley JA, Martin PJ, Babu SR.
Spence JK, et al.
Pharm Dev Technol. 2005;10(4):451-60. doi: 10.1080/10837450500299636.
Pharm Dev Technol. 2005.
PMID: 16370174
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