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Page 1
Gradual Rarefaction of Hematopoietic Precursors and Atrophy in a Depleted microRNA 29a, b and c Environment.
Kauffman L, Balatti V, Cascione L, Fadda P, Racke F, Santhanam R, Costinean S. Kauffman L, et al. Among authors: santhanam r. PLoS One. 2015 Jul 6;10(7):e0131981. doi: 10.1371/journal.pone.0131981. eCollection 2015. PLoS One. 2015. Retraction in: PLoS One. 2017 Oct 30;12(10):e0187454. doi: 10.1371/journal.pone.0187454 PMID: 26147501 Free PMC article. Retracted.
Regulation of acute graft-versus-host disease by microRNA-155.
Ranganathan P, Heaphy CE, Costinean S, Stauffer N, Na C, Hamadani M, Santhanam R, Mao C, Taylor PA, Sandhu S, He G, Shana'ah A, Nuovo GJ, Lagana A, Cascione L, Obad S, Broom O, Kauppinen S, Byrd JC, Caligiuri M, Perrotti D, Hadley GA, Marcucci G, Devine SM, Blazar BR, Croce CM, Garzon R. Ranganathan P, et al. Among authors: santhanam r. Blood. 2012 May 17;119(20):4786-97. doi: 10.1182/blood-2011-10-387522. Epub 2012 Mar 9. Blood. 2012. PMID: 22408260 Free PMC article.
MicroRNAs bind to Toll-like receptors to induce prometastatic inflammatory response.
Fabbri M, Paone A, Calore F, Galli R, Gaudio E, Santhanam R, Lovat F, Fadda P, Mao C, Nuovo GJ, Zanesi N, Crawford M, Ozer GH, Wernicke D, Alder H, Caligiuri MA, Nana-Sinkam P, Perrotti D, Croce CM. Fabbri M, et al. Among authors: santhanam r. Proc Natl Acad Sci U S A. 2012 Jul 31;109(31):E2110-6. doi: 10.1073/pnas.1209414109. Epub 2012 Jul 2. Proc Natl Acad Sci U S A. 2012. PMID: 22753494 Free PMC article.
Aberrant overexpression of IL-15 initiates large granular lymphocyte leukemia through chromosomal instability and DNA hypermethylation.
Mishra A, Liu S, Sams GH, Curphey DP, Santhanam R, Rush LJ, Schaefer D, Falkenberg LG, Sullivan L, Jaroncyk L, Yang X, Fisk H, Wu LC, Hickey C, Chandler JC, Wu YZ, Heerema NA, Chan KK, Perrotti D, Zhang J, Porcu P, Racke FK, Garzon R, Lee RJ, Marcucci G, Caligiuri MA. Mishra A, et al. Among authors: santhanam r. Cancer Cell. 2012 Nov 13;22(5):645-55. doi: 10.1016/j.ccr.2012.09.009. Cancer Cell. 2012. PMID: 23153537 Free PMC article.
miR-155 targets histone deacetylase 4 (HDAC4) and impairs transcriptional activity of B-cell lymphoma 6 (BCL6) in the Eμ-miR-155 transgenic mouse model.
Sandhu SK, Volinia S, Costinean S, Galasso M, Neinast R, Santhanam R, Parthun MR, Perrotti D, Marcucci G, Garzon R, Croce CM. Sandhu SK, et al. Among authors: santhanam r. Proc Natl Acad Sci U S A. 2012 Dec 4;109(49):20047-52. doi: 10.1073/pnas.1213764109. Epub 2012 Nov 19. Proc Natl Acad Sci U S A. 2012. PMID: 23169640 Free PMC article.
Identification of novel posttranscriptional targets of the BCR/ABL oncoprotein by ribonomics: requirement of E2F3 for BCR/ABL leukemogenesis.
Eiring AM, Neviani P, Santhanam R, Oaks JJ, Chang JS, Notari M, Willis W, Gambacorti-Passerini C, Volinia S, Marcucci G, Caligiuri MA, Leone GW, Perrotti D. Eiring AM, et al. Among authors: santhanam r. Blood. 2008 Jan 15;111(2):816-28. doi: 10.1182/blood-2007-05-090472. Epub 2007 Oct 9. Blood. 2008. PMID: 17925491 Free PMC article.
Eradicating acute myeloid leukemia in a Mll(PTD/wt):Flt3(ITD/wt) murine model: a path to novel therapeutic approaches for human disease.
Bernot KM, Nemer JS, Santhanam R, Liu S, Zorko NA, Whitman SP, Dickerson KE, Zhang M, Yang X, McConnell KK, Ahmed EH, Muñoz MR, Siebenaler RF, Marcucci GG, Mundy-Bosse BL, Brook DL, Garman S, Dorrance AM, Zhang X, Zhang J, Lee RJ, Blum W, Caligiuri MA, Marcucci G. Bernot KM, et al. Among authors: santhanam r. Blood. 2013 Nov 28;122(23):3778-83. doi: 10.1182/blood-2013-06-507426. Epub 2013 Oct 1. Blood. 2013. PMID: 24085765 Free PMC article.
Lenalidomide-mediated enhanced translation of C/EBPα-p30 protein up-regulates expression of the antileukemic microRNA-181a in acute myeloid leukemia.
Hickey CJ, Schwind S, Radomska HS, Dorrance AM, Santhanam R, Mishra A, Wu YZ, Alachkar H, Maharry K, Nicolet D, Mrózek K, Walker A, Eiring AM, Whitman SP, Becker H, Perrotti D, Wu LC, Zhao X, Fehniger TA, Vij R, Byrd JC, Blum W, Lee LJ, Caligiuri MA, Bloomfield CD, Garzon R, Marcucci G. Hickey CJ, et al. Among authors: santhanam r. Blood. 2013 Jan 3;121(1):159-69. doi: 10.1182/blood-2012-05-428573. Epub 2012 Oct 25. Blood. 2013. PMID: 23100311 Free PMC article.
Intronic miR-3151 within BAALC drives leukemogenesis by deregulating the TP53 pathway.
Eisfeld AK, Schwind S, Patel R, Huang X, Santhanam R, Walker CJ, Markowitz J, Hoag KW, Jarvinen TM, Leffel B, Perrotti D, Carson WE 3rd, Marcucci G, Bloomfield CD, de la Chapelle A. Eisfeld AK, et al. Among authors: santhanam r. Sci Signal. 2014 Apr 15;7(321):ra36. doi: 10.1126/scisignal.2004762. Sci Signal. 2014. PMID: 24736457 Free PMC article.
130 results