Shi XN - Search Results

1

In Silico Identification and In Vitro and In Vivo Validation of Anti-Psychotic Drug Fluspirilene as a Potential CDK2 Inhibitor and a Candidate Anti-Cancer Drug.

Shi XN, Li H, Yao H, Liu X, Li L, Leung KS, Kung HF, Lu D, Wong MH, Lin MC. Shi XN, et al. PLoS One. 2015 Jul 6;10(7):e0132072. doi: 10.1371/journal.pone.0132072. eCollection 2015. PLoS One. 2015. PMID: 26147897 Free PMC article.

2

Adapalene inhibits the activity of cyclin-dependent kinase 2 in colorectal carcinoma.

Shi XN, Li H, Yao H, Liu X, Li L, Leung KS, Kung HF, Lin MC. Shi XN, et al. Mol Med Rep. 2015 Nov;12(5):6501-8. doi: 10.3892/mmr.2015.4310. Epub 2015 Sep 10. Mol Med Rep. 2015. PMID: 26398439 Free PMC article.

3

In silico prediction and in vitro and in vivo validation of acaricide fluazuron as a potential inhibitor of FGFR3 and a candidate anticancer drug for bladder carcinoma.

Ke K, Li H, Yao H, Shi XN, Dong C, Zhu Y, Liu X, Li L, Leung KS, Wong MH, Liu XD, Kung HF, Lin MC. Ke K, et al. Among authors: shi xn. Chem Biol Drug Des. 2017 Apr;89(4):505-513. doi: 10.1111/cbdd.12872. Epub 2016 Nov 2. Chem Biol Drug Des. 2017. PMID: 27664399

4

Econazole nitrate inhibits PI3K activity and promotes apoptosis in lung cancer cells.

Dong C, Yang R, Li H, Ke K, Luo C, Yang F, Shi XN, Zhu Y, Liu X, Wong MH, Lin G, Wang X, Leung KS, Kung HF, Chen C, Lin MC. Dong C, et al. Among authors: shi xn. Sci Rep. 2017 Dec 21;7(1):17987. doi: 10.1038/s41598-017-18178-0. Sci Rep. 2017. PMID: 29269744 Free PMC article.

5

Discovery of rafoxanide as a dual CDK4/6 inhibitor for the treatment of skin cancer.

Shi X, Li H, Shi A, Yao H, Ke K, Dong C, Zhu Y, Qin Y, Ding Y, He YH, Liu X, Li L, Lei L, Hai Q, Chen W, Leung KS, Wong MH, Kung HF, Lin MC. Shi X, et al. Oncol Rep. 2018 Sep;40(3):1592-1600. doi: 10.3892/or.2018.6533. Epub 2018 Jun 27. Oncol Rep. 2018. PMID: 29956794

6

The antipsychotic agent flupentixol is a new PI3K inhibitor and potential anticancer drug for lung cancer.

Dong C, Chen Y, Li H, Yang Y, Zhang H, Ke K, Shi XN, Liu X, Li L, Ma J, Kung HF, Chen C, Lin MC. Dong C, et al. Among authors: shi xn. Int J Biol Sci. 2019 Jun 2;15(7):1523-1532. doi: 10.7150/ijbs.32625. eCollection 2019. Int J Biol Sci. 2019. PMID: 31337981 Free PMC article.

7

Discovery of vanoxerine dihydrochloride as a CDK2/4/6 triple-inhibitor for the treatment of human hepatocellular carcinoma.

Zhu Y, Ke KB, Xia ZK, Li HJ, Su R, Dong C, Zhou FM, Wang L, Chen R, Wu SG, Zhao H, Gu P, Leung KS, Wong MH, Lu G, Zhang JY, Jiang BH, Qiu JG, Shi XN, Lin MC. Zhu Y, et al. Among authors: shi xn. Mol Med. 2021 Feb 12;27(1):15. doi: 10.1186/s10020-021-00269-4. Mol Med. 2021. PMID: 33579185 Free PMC article.

8

Discovery of a New CDK4/6 and PI3K/AKT Multiple Kinase Inhibitor Aminoquinol for the Treatment of Hepatocellular Carcinoma.

Xia ZK, Wang W, Qiu JG, Shi XN, Li HJ, Chen R, Ke KB, Dong C, Zhu Y, Wu SG, Zhang RP, Meng ZR, Zhao H, Gu P, Leung KS, Wong MH, Liu XD, Zhou FM, Zhang JY, Yao YT, Wang SJ, Zhang CY, Qin YR, Lin MC, Jiang BH. Xia ZK, et al. Among authors: shi xn. Front Pharmacol. 2021 Jul 15;12:691769. doi: 10.3389/fphar.2021.691769. eCollection 2021. Front Pharmacol. 2021. PMID: 34335258 Free PMC article.

9

Polyphyllin I, a lethal partner of Palbociclib, suppresses non-small cell lung cancer through activation of p21/CDK2/Rb pathway in vitro and in vivo.

Shen Z, Wang J, Ke K, Chen R, Zuo A, Zhang R, Wan W, Xie X, Li X, Song N, Fu H, Zhang Z, Cai E, Shen J, Zhang Q, Shi X. Shen Z, et al. Cell Cycle. 2021 Dec;20(23):2494-2506. doi: 10.1080/15384101.2021.1991121. Epub 2021 Oct 17. Cell Cycle. 2021. Retraction in: Cell Cycle. 2024 Jul 4:1. doi: 10.1080/15384101.2024.2370721 PMID: 34658297 Free PMC article. Retracted.

10

MW-19, a dihydropyrazole derivative, induces human triple-negative breast cancer cell apoptosis by targeting apoptosis-related pathways.

Zou N, Wu R, Wu Z, Zhang C, Zhang H, Mo Q, Ju M, Shi X, Mao Z, Wan C. Zou N, et al. Chem Biol Drug Des. 2024 Jul;104(1):e14589. doi: 10.1111/cbdd.14589. Chem Biol Drug Des. 2024. PMID: 39031926

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