Medema RH - Search Results

1

OTUB1 inhibits the ubiquitination and degradation of FOXM1 in breast cancer and epirubicin resistance.

Karunarathna U, Kongsema M, Zona S, Gong C, Cabrera E, Gomes AR, Man EP, Khongkow P, Tsang JW, Khoo US, Medema RH, Freire R, Lam EW. Karunarathna U, et al. Among authors: medema rh. Oncogene. 2016 Mar 17;35(11):1433-44. doi: 10.1038/onc.2015.208. Epub 2015 Jul 6. Oncogene. 2016. PMID: 26148240 Free PMC article.

2

Inhibition of the phosphoinositide 3-kinase pathway induces a senescence-like arrest mediated by p27Kip1.

Collado M, Medema RH, Garcia-Cao I, Dubuisson ML, Barradas M, Glassford J, Rivas C, Burgering BM, Serrano M, Lam EW. Collado M, et al. Among authors: medema rh. J Biol Chem. 2000 Jul 21;275(29):21960-8. doi: 10.1074/jbc.M000759200. J Biol Chem. 2000. PMID: 10791951 Free article.

3

Forkhead transcription factor FKHR-L1 modulates cytokine-dependent transcriptional regulation of p27(KIP1).

Dijkers PF, Medema RH, Pals C, Banerji L, Thomas NS, Lam EW, Burgering BM, Raaijmakers JA, Lammers JW, Koenderman L, Coffer PJ. Dijkers PF, et al. Among authors: medema rh. Mol Cell Biol. 2000 Dec;20(24):9138-48. doi: 10.1128/MCB.20.24.9138-9148.2000. Mol Cell Biol. 2000. PMID: 11094066 Free PMC article.

4

H2O2 induces a transient multi-phase cell cycle arrest in mouse fibroblasts through modulating cyclin D and p21Cip1 expression.

Barnouin K, Dubuisson ML, Child ES, Fernandez de Mattos S, Glassford J, Medema RH, Mann DJ, Lam EW. Barnouin K, et al. Among authors: medema rh. J Biol Chem. 2002 Apr 19;277(16):13761-70. doi: 10.1074/jbc.M111123200. Epub 2002 Feb 4. J Biol Chem. 2002. PMID: 11827966 Free article.

5

Control of cell cycle exit and entry by protein kinase B-regulated forkhead transcription factors.

Kops GJ, Medema RH, Glassford J, Essers MA, Dijkers PF, Coffer PJ, Lam EW, Burgering BM. Kops GJ, et al. Among authors: medema rh. Mol Cell Biol. 2002 Apr;22(7):2025-36. doi: 10.1128/MCB.22.7.2025-2036.2002. Mol Cell Biol. 2002. PMID: 11884591 Free PMC article.

6

Cell cycle inhibition by FoxO forkhead transcription factors involves downregulation of cyclin D.

Schmidt M, Fernandez de Mattos S, van der Horst A, Klompmaker R, Kops GJ, Lam EW, Burgering BM, Medema RH. Schmidt M, et al. Among authors: medema rh. Mol Cell Biol. 2002 Nov;22(22):7842-52. doi: 10.1128/MCB.22.22.7842-7852.2002. Mol Cell Biol. 2002. PMID: 12391153 Free PMC article.

7

FoxO3a transcriptional regulation of Bim controls apoptosis in paclitaxel-treated breast cancer cell lines.

Sunters A, Fernández de Mattos S, Stahl M, Brosens JJ, Zoumpoulidou G, Saunders CA, Coffer PJ, Medema RH, Coombes RC, Lam EW. Sunters A, et al. Among authors: medema rh. J Biol Chem. 2003 Dec 12;278(50):49795-805. doi: 10.1074/jbc.M309523200. Epub 2003 Oct 3. J Biol Chem. 2003. PMID: 14527951 Free article.

8

Direct transcriptional regulation of Bim by FoxO3a mediates STI571-induced apoptosis in Bcr-Abl-expressing cells.

Essafi A, Fernández de Mattos S, Hassen YA, Soeiro I, Mufti GJ, Thomas NS, Medema RH, Lam EW. Essafi A, et al. Among authors: medema rh. Oncogene. 2005 Mar 31;24(14):2317-29. doi: 10.1038/sj.onc.1208421. Oncogene. 2005. PMID: 15688014

9

Polo-like kinase-1 controls proteasome-dependent degradation of Claspin during checkpoint recovery.

Mamely I, van Vugt MA, Smits VA, Semple JI, Lemmens B, Perrakis A, Medema RH, Freire R. Mamely I, et al. Among authors: medema rh. Curr Biol. 2006 Oct 10;16(19):1950-5. doi: 10.1016/j.cub.2006.08.026. Epub 2006 Aug 24. Curr Biol. 2006. PMID: 16934469 Free article.

10

Claspin: timing the cell cycle arrest when the genome is damaged.

Freire R, van Vugt MA, Mamely I, Medema RH. Freire R, et al. Among authors: medema rh. Cell Cycle. 2006 Dec;5(24):2831-4. doi: 10.4161/cc.5.24.3559. Epub 2006 Dec 15. Cell Cycle. 2006. PMID: 17172868 Review.

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