Lefebvre V - Search Results

1

The transcription factors SOX9 and SOX5/SOX6 cooperate genome-wide through super-enhancers to drive chondrogenesis.

Liu CF, Lefebvre V. Liu CF, et al. Among authors: lefebvre v. Nucleic Acids Res. 2015 Sep 30;43(17):8183-203. doi: 10.1093/nar/gkv688. Epub 2015 Jul 6. Nucleic Acids Res. 2015. PMID: 26150426 Free PMC article.

2

L-Sox5, Sox6 and Sox9 control essential steps of the chondrocyte differentiation pathway.

Lefebvre V, Behringer RR, de Crombrugghe B. Lefebvre V, et al. Osteoarthritis Cartilage. 2001;9 Suppl A:S69-75. doi: 10.1053/joca.2001.0447. Osteoarthritis Cartilage. 2001. PMID: 11680692 Free article.

3

Toward understanding the functions of the two highly related Sox5 and Sox6 genes.

Lefebvre V. Lefebvre V. J Bone Miner Metab. 2002;20(3):121-30. doi: 10.1007/s007740200017. J Bone Miner Metab. 2002. PMID: 11984693 Review. No abstract available.

4

Sox5 and Sox6 are required for notochord extracellular matrix sheath formation, notochord cell survival and development of the nucleus pulposus of intervertebral discs.

Smits P, Lefebvre V. Smits P, et al. Among authors: lefebvre v. Development. 2003 Mar;130(6):1135-48. doi: 10.1242/dev.00331. Development. 2003. PMID: 12571105

5

Sox5 and Sox6 are needed to develop and maintain source, columnar, and hypertrophic chondrocytes in the cartilage growth plate.

Smits P, Dy P, Mitra S, Lefebvre V. Smits P, et al. Among authors: lefebvre v. J Cell Biol. 2004 Mar 1;164(5):747-58. doi: 10.1083/jcb.200312045. J Cell Biol. 2004. PMID: 14993235 Free PMC article.

6

Transcriptional control of chondrocyte fate and differentiation.

Lefebvre V, Smits P. Lefebvre V, et al. Birth Defects Res C Embryo Today. 2005 Sep;75(3):200-12. doi: 10.1002/bdrc.20048. Birth Defects Res C Embryo Today. 2005. PMID: 16187326 Review.

7

Generation of mice harboring a Sox6 conditional null allele.

Dumitriu B, Dy P, Smits P, Lefebvre V. Dumitriu B, et al. Among authors: lefebvre v. Genesis. 2006 May;44(5):219-24. doi: 10.1002/dvg.20210. Genesis. 2006. PMID: 16652367

8

The three SoxC proteins--Sox4, Sox11 and Sox12--exhibit overlapping expression patterns and molecular properties.

Dy P, Penzo-Méndez A, Wang H, Pedraza CE, Macklin WB, Lefebvre V. Dy P, et al. Among authors: lefebvre v. Nucleic Acids Res. 2008 May;36(9):3101-17. doi: 10.1093/nar/gkn162. Epub 2008 Apr 10. Nucleic Acids Res. 2008. PMID: 18403418 Free PMC article.

9

Generation of mice harboring a Sox5 conditional null allele.

Dy P, Han Y, Lefebvre V. Dy P, et al. Among authors: lefebvre v. Genesis. 2008 Jun;46(6):294-9. doi: 10.1002/dvg.20392. Genesis. 2008. PMID: 18543318

10

L-Sox5 and Sox6 drive expression of the aggrecan gene in cartilage by securing binding of Sox9 to a far-upstream enhancer.

Han Y, Lefebvre V. Han Y, et al. Among authors: lefebvre v. Mol Cell Biol. 2008 Aug;28(16):4999-5013. doi: 10.1128/MCB.00695-08. Epub 2008 Jun 16. Mol Cell Biol. 2008. PMID: 18559420 Free PMC article.

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