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Development of Fluorine-18 Labeled Metabolically Activated Tracers for Imaging of Drug Efflux Transporters with Positron Emission Tomography.
Sander K, Galante E, Gendron T, Yiannaki E, Patel N, Kalber TL, Badar A, Robson M, Johnson SP, Bauer F, Mairinger S, Stanek J, Wanek T, Kuntner C, Kottke T, Weizel L, Dickens D, Erlandsson K, Hutton BF, Lythgoe MF, Stark H, Langer O, Koepp M, Årstad E. Sander K, et al. Among authors: langer o. J Med Chem. 2015 Aug 13;58(15):6058-80. doi: 10.1021/acs.jmedchem.5b00652. Epub 2015 Jul 24. J Med Chem. 2015. PMID: 26161456 Free article.
A positron emission tomography microdosing study with a potential antiamyloid drug in healthy volunteers and patients with Alzheimer's disease.
Bauer M, Langer O, Dal-Bianco P, Karch R, Brunner M, Abrahim A, Lanzenberger R, Hofmann A, Joukhadar C, Carminati P, Ghirardi O, Piovesan P, Forloni G, Corrado ME, Lods N, Dudczak R, Auff E, Kletter K, Müller M. Bauer M, et al. Among authors: langer o. Clin Pharmacol Ther. 2006 Sep;80(3):216-27. doi: 10.1016/j.clpt.2006.05.007. Clin Pharmacol Ther. 2006. PMID: 16952488 Clinical Trial.
Pharmacoresistance in epilepsy: a pilot PET study with the P-glycoprotein substrate R-[(11)C]verapamil.
Langer O, Bauer M, Hammers A, Karch R, Pataraia E, Koepp MJ, Abrahim A, Luurtsema G, Brunner M, Sunder-Plassmann R, Zimprich F, Joukhadar C, Gentzsch S, Dudczak R, Kletter K, Müller M, Baumgartner C. Langer O, et al. Epilepsia. 2007 Sep;48(9):1774-1784. doi: 10.1111/j.1528-1167.2007.01116.x. Epub 2007 May 1. Epilepsia. 2007. PMID: 17484754 Free article.
Synthesis and small-animal positron emission tomography evaluation of [11C]-elacridar as a radiotracer to assess the distribution of P-glycoprotein at the blood-brain barrier.
Dörner B, Kuntner C, Bankstahl JP, Bankstahl M, Stanek J, Wanek T, Stundner G, Mairinger S, Löscher W, Müller M, Langer O, Erker T. Dörner B, et al. Among authors: langer o. J Med Chem. 2009 Oct 8;52(19):6073-82. doi: 10.1021/jm900940f. J Med Chem. 2009. PMID: 19711894 Free PMC article.
393 results