Sausville E - Search Results

1

Targeting of mTOR catalytic site inhibits multiple steps of the HIV-1 lifecycle and suppresses HIV-1 viremia in humanized mice.

Heredia A, Le N, Gartenhaus RB, Sausville E, Medina-Moreno S, Zapata JC, Davis C, Gallo RC, Redfield RR. Heredia A, et al. Among authors: sausville e. Proc Natl Acad Sci U S A. 2015 Jul 28;112(30):9412-7. doi: 10.1073/pnas.1511144112. Epub 2015 Jul 13. Proc Natl Acad Sci U S A. 2015. PMID: 26170311 Free PMC article.

2

Targeting of CDK9 with indirubin 3'-monoxime safely and durably reduces HIV viremia in chronically infected humanized mice.

Medina-Moreno S, Dowling TC, Zapata JC, Le NM, Sausville E, Bryant J, Redfield RR, Heredia A. Medina-Moreno S, et al. Among authors: sausville e. PLoS One. 2017 Aug 17;12(8):e0183425. doi: 10.1371/journal.pone.0183425. eCollection 2017. PLoS One. 2017. PMID: 28817720 Free PMC article.

3

Disparate effects of cytotoxic chemotherapy on the antiviral activity of antiretroviral therapy: implications for treatments of HIV-infected cancer patients.

Medina-Moreno S, Zapata JC, Cottrell ML, Le NM, Tao S, Bryant J, Sausville E, Schinazi RF, Kashuba AD, Redfield RR, Heredia A. Medina-Moreno S, et al. Among authors: sausville e. Antivir Ther. 2019;24(3):177-186. doi: 10.3851/IMP3285. Antivir Ther. 2019. PMID: 30574873 Free PMC article.

4

Akt plays a central role in sarcomagenesis induced by Kaposi's sarcoma herpesvirus-encoded G protein-coupled receptor.

Sodhi A, Montaner S, Patel V, Gómez-Román JJ, Li Y, Sausville EA, Sawai ET, Gutkind JS. Sodhi A, et al. Proc Natl Acad Sci U S A. 2004 Apr 6;101(14):4821-6. doi: 10.1073/pnas.0400835101. Epub 2004 Mar 26. Proc Natl Acad Sci U S A. 2004. PMID: 15047889 Free PMC article.

5

Phospho-p70S6K/p85S6K and cdc2/cdk1 are novel targets for diffuse large B-cell lymphoma combination therapy.

Zhao MY, Auerbach A, D'Costa AM, Rapoport AP, Burger AM, Sausville EA, Stass SA, Jiang F, Sands AM, Aguilera N, Zhao XF. Zhao MY, et al. Clin Cancer Res. 2009 Mar 1;15(5):1708-20. doi: 10.1158/1078-0432.CCR-08-1543. Epub 2009 Feb 17. Clin Cancer Res. 2009. PMID: 19223503

6

Preclinical modeling of combination treatments: fantasy or requirement?

Decker S, Sausville EA. Decker S, et al. Ann N Y Acad Sci. 2005 Nov;1059:61-9. doi: 10.1196/annals.1339.024. Ann N Y Acad Sci. 2005. PMID: 16382044 Review.

7

Azodicarbonamide inhibits HIV-1 replication by targeting the nucleocapsid protein.

Rice WG, Turpin JA, Huang M, Clanton D, Buckheit RW Jr, Covell DG, Wallqvist A, McDonnell NB, DeGuzman RN, Summers MF, Zalkow L, Bader JP, Haugwitz RD, Sausville EA. Rice WG, et al. Among authors: sausville ea. Nat Med. 1997 Mar;3(3):341-5. doi: 10.1038/nm0397-341. Nat Med. 1997. PMID: 9055865

8

Cell cycle regulatory kinase modulators: interim progress and issues.

Sausville EA. Sausville EA. Curr Top Med Chem. 2005;5(12):1109-17. doi: 10.2174/156802605774370874. Curr Top Med Chem. 2005. PMID: 16248786 Review.

9

Interactive effects of HDAC inhibitors and TRAIL on apoptosis are associated with changes in mitochondrial functions and expressions of cell cycle regulatory genes in multiple myeloma.

Fandy TE, Shankar S, Ross DD, Sausville E, Srivastava RK. Fandy TE, et al. Among authors: sausville e. Neoplasia. 2005 Jul;7(7):646-57. doi: 10.1593/neo.04655. Neoplasia. 2005. PMID: 16026644 Free PMC article.

10

Synthesis, characterization and antineoplastic activity of bis-aziridinyl dimeric naphthoquinone - A novel class of compounds with potent activity against acute myeloid leukemia cells.

Carter-Cooper BA, Fletcher S, Ferraris D, Choi EY, Kronfli D, Dash S, Truong P, Sausville EA, Lapidus RG, Emadi A. Carter-Cooper BA, et al. Bioorg Med Chem Lett. 2017 Jan 1;27(1):6-10. doi: 10.1016/j.bmcl.2016.11.045. Epub 2016 Nov 17. Bioorg Med Chem Lett. 2017. PMID: 27890379 Free PMC article.

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