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Page 1
Role of Pin1 protein in the pathogenesis of nonalcoholic steatohepatitis in a rodent model.
Nakatsu Y, Otani Y, Sakoda H, Zhang J, Guo Y, Okubo H, Kushiyama A, Fujishiro M, Kikuch T, Fukushima T, Ohno H, Tsuchiya Y, Kamata H, Nagamachi A, Inaba T, Nishimura F, Katagiri H, Takahashi S, Kurihara H, Uchida T, Asano T. Nakatsu Y, et al. Among authors: okubo h. J Biol Chem. 2012 Dec 28;287(53):44526-35. doi: 10.1074/jbc.M112.397133. Epub 2012 Oct 29. J Biol Chem. 2012. PMID: 23112047 Free PMC article.
Lactobacillus casei strain Shirota protects against nonalcoholic steatohepatitis development in a rodent model.
Okubo H, Sakoda H, Kushiyama A, Fujishiro M, Nakatsu Y, Fukushima T, Matsunaga Y, Kamata H, Asahara T, Yoshida Y, Chonan O, Iwashita M, Nishimura F, Asano T. Okubo H, et al. Am J Physiol Gastrointest Liver Physiol. 2013 Dec;305(12):G911-8. doi: 10.1152/ajpgi.00225.2013. Epub 2013 Oct 10. Am J Physiol Gastrointest Liver Physiol. 2013. PMID: 24113768 Free article.
Mosapride citrate improves nonalcoholic steatohepatitis with increased fecal lactic acid bacteria and plasma glucagon-like peptide-1 level in a rodent model.
Okubo H, Nakatsu Y, Sakoda H, Kushiyama A, Fujishiro M, Fukushima T, Matsunaga Y, Ohno H, Yoneda M, Kamata H, Shinjo T, Iwashita M, Nishimura F, Asano T. Okubo H, et al. Am J Physiol Gastrointest Liver Physiol. 2015 Jan 15;308(2):G151-8. doi: 10.1152/ajpgi.00198.2014. Epub 2014 Nov 26. Am J Physiol Gastrointest Liver Physiol. 2015. PMID: 25428903 Free article.
Involvement of resistin-like molecule β in the development of methionine-choline deficient diet-induced non-alcoholic steatohepatitis in mice.
Okubo H, Kushiyama A, Sakoda H, Nakatsu Y, Iizuka M, Taki N, Fujishiro M, Fukushima T, Kamata H, Nagamachi A, Inaba T, Nishimura F, Katagiri H, Asahara T, Yoshida Y, Chonan O, Encinas J, Asano T. Okubo H, et al. Sci Rep. 2016 Jan 28;6:20157. doi: 10.1038/srep20157. Sci Rep. 2016. PMID: 26818807 Free PMC article.
4F2hc stabilizes GLUT1 protein and increases glucose transport activity.
Ohno H, Nakatsu Y, Sakoda H, Kushiyama A, Ono H, Fujishiro M, Otani Y, Okubo H, Yoneda M, Fukushima T, Tsuchiya Y, Kamata H, Nishimura F, Kurihara H, Katagiri H, Oka Y, Asano T. Ohno H, et al. Among authors: okubo h. Am J Physiol Cell Physiol. 2011 May;300(5):C1047-54. doi: 10.1152/ajpcell.00416.2010. Epub 2011 Jan 26. Am J Physiol Cell Physiol. 2011. PMID: 21270293 Free article.
Xanthine oxidoreductase is involved in macrophage foam cell formation and atherosclerosis development.
Kushiyama A, Okubo H, Sakoda H, Kikuchi T, Fujishiro M, Sato H, Kushiyama S, Iwashita M, Nishimura F, Fukushima T, Nakatsu Y, Kamata H, Kawazu S, Higashi Y, Kurihara H, Asano T. Kushiyama A, et al. Among authors: okubo h. Arterioscler Thromb Vasc Biol. 2012 Feb;32(2):291-8. doi: 10.1161/ATVBAHA.111.234559. Epub 2011 Nov 17. Arterioscler Thromb Vasc Biol. 2012. PMID: 22095983
Integrator complex plays an essential role in adipose differentiation.
Otani Y, Nakatsu Y, Sakoda H, Fukushima T, Fujishiro M, Kushiyama A, Okubo H, Tsuchiya Y, Ohno H, Takahashi S, Nishimura F, Kamata H, Katagiri H, Asano T. Otani Y, et al. Among authors: okubo h. Biochem Biophys Res Commun. 2013 May 3;434(2):197-202. doi: 10.1016/j.bbrc.2013.03.029. Epub 2013 Mar 21. Biochem Biophys Res Commun. 2013. PMID: 23523797
Par14 protein associates with insulin receptor substrate 1 (IRS-1), thereby enhancing insulin-induced IRS-1 phosphorylation and metabolic actions.
Zhang J, Nakatsu Y, Shinjo T, Guo Y, Sakoda H, Yamamotoya T, Otani Y, Okubo H, Kushiyama A, Fujishiro M, Fukushima T, Tsuchiya Y, Kamata H, Iwashita M, Nishimura F, Katagiri H, Takahashi S, Kurihara H, Uchida T, Asano T. Zhang J, et al. Among authors: okubo h. J Biol Chem. 2013 Jul 12;288(28):20692-701. doi: 10.1074/jbc.M113.485730. Epub 2013 May 29. J Biol Chem. 2013. PMID: 23720771 Free PMC article.
Gut Microbiota as a Therapeutic Target for Metabolic Disorders.
Okubo H, Nakatsu Y, Kushiyama A, Yamamotoya T, Matsunaga Y, Inoue MK, Fujishiro M, Sakoda H, Ohno H, Yoneda M, Ono H, Asano T. Okubo H, et al. Curr Med Chem. 2018;25(9):984-1001. doi: 10.2174/0929867324666171009121702. Curr Med Chem. 2018. PMID: 28990516 Review.
537 results