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Loss of lysosomal acid lipase results in mitochondrial dysfunction and fiber switch in skeletal muscles of mice.
Akhmetshina A, Bianco V, Bradić I, Korbelius M, Pirchheim A, Kuentzel KB, Eichmann TO, Hinteregger H, Kolb D, Habisch H, Liesinger L, Madl T, Sattler W, Radović B, Sedej S, Birner-Gruenberger R, Vujić N, Kratky D. Akhmetshina A, et al. Among authors: sedej s. Mol Metab. 2024 Jan;79:101869. doi: 10.1016/j.molmet.2023.101869. Epub 2023 Dec 30. Mol Metab. 2024. PMID: 38160938 Free PMC article.
Metabolic control of mitophagy.
Zimmermann A, Madeo F, Diwan A, Sadoshima J, Sedej S, Kroemer G, Abdellatif M. Zimmermann A, et al. Among authors: sedej s. Eur J Clin Invest. 2024 Apr;54(4):e14138. doi: 10.1111/eci.14138. Epub 2023 Dec 1. Eur J Clin Invest. 2024. PMID: 38041247 Review.
Cardiac PI3K p110α attenuation delays aging and extends lifespan.
Abdellatif M, Eisenberg T, Heberle AM, Thedieck K, Kroemer G, Sedej S. Abdellatif M, et al. Among authors: sedej s. Cell Stress. 2022 Aug 8;6(8):72-75. doi: 10.15698/cst2022.08.270. eCollection 2022 Aug. Cell Stress. 2022. PMID: 36447531 Free PMC article.
Hallmarks of cardiovascular ageing.
Abdellatif M, Rainer PP, Sedej S, Kroemer G. Abdellatif M, et al. Among authors: sedej s. Nat Rev Cardiol. 2023 Nov;20(11):754-777. doi: 10.1038/s41569-023-00881-3. Epub 2023 May 16. Nat Rev Cardiol. 2023. PMID: 37193857 Review.
JTV519 (K201) reduces sarcoplasmic reticulum Ca²⁺ leak and improves diastolic function in vitro in murine and human non-failing myocardium.
Sacherer M, Sedej S, Wakuła P, Wallner M, Vos MA, Kockskämper J, Stiegler P, Sereinigg M, von Lewinski D, Antoons G, Pieske BM, Heinzel FR; CONTICA investigators. Sacherer M, et al. Among authors: sedej s. Br J Pharmacol. 2012 Oct;167(3):493-504. doi: 10.1111/j.1476-5381.2012.01995.x. Br J Pharmacol. 2012. PMID: 22509897 Free PMC article.
71 results